Gene targeting and the biology of learning and memory

Silva, A. J., Smith, A. M., Giese, K. P. (December 1997) Gene targeting and the biology of learning and memory. Annual Review of Genetics, 31. pp. 527-46. ISSN 0066-4197 (Print)

DOI: 10.1146/annurev.genet.31.1.527


The general goal of genetic studies of learning and memory is to develop and test theories that explain the animal's behavior in neuroanatomical, neurophysiological, cellular, and molecular terms. In this review we describe the role that gene targeting and other transgenic techniques have had in the study of mammalian learning and memory. We focus especially on the hippocampus, a brain structure that is thought to be central to the processing and temporary storage of complex information. We also discuss the main issues that confront this young field, as well as our vision for its future.

Item Type: Paper
Uncontrolled Keywords: Animals Forecasting Gene Targeting Humans Learning Memory
Subjects: bioinformatics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organism description > animal behavior > learning
organism description > animal behavior > memory
CSHL Authors:
Communities: CSHL labs
Depositing User: Kathleen Darby
Date: December 1997
Date Deposited: 07 May 2014 15:39
Last Modified: 07 May 2014 15:39
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