Shields, J. M., Der, C. J., Powers, S.
(2001)
Identification of Ras-regulated genes by representational difference analysis.
Methods in Enzymology, 332.
pp. 221-32.
ISSN 00766879 (ISSN)
Abstract
In conclusion, RDA provides a fast, technically simple, and inexpensive way to characterize genes aberrantly expressed due to Ras transformation. The identification and characterization of these genes may provide insight not only into the mechanism by which Ras causes transformation, but also may identify novel targets for rational drug design and development of anticancer drugs.
| Item Type: |
Paper
|
| Uncontrolled Keywords: |
Animals
Base Sequence
Cell Line
Cloning, Molecular
DNA Primers/genetics
DNA, Complementary/genetics/isolation & purification
Down-Regulation
Gene Expression Regulation
*Genes, ras
*Genetic Techniques
Nucleic Acid Hybridization
Polymerase Chain Reaction
RNA, Messenger/genetics/isolation & purification
Rats |
| Subjects: |
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > G protein
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > G protein > Ras |
| CSHL Authors: |
|
| Communities: |
CSHL labs > Powers lab |
| Depositing User: |
Matt Covey
|
| Date: |
2001 |
| Date Deposited: |
25 Feb 2014 21:37 |
| Last Modified: |
25 Feb 2014 21:37 |
| Related URLs: |
|
| URI: |
https://repository.cshl.edu/id/eprint/29530 |
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