Uchida, N., Takahashi, Y. K., Tanifuji, M., Mori, K. (October 2000) Odor maps in the mammalian olfactory bulb: domain organization and odorant structural features. Nature Neuroscience, 3 (10). pp. 1035-1043. ISSN 1097-6256
Abstract
Psychophysical studies indicate that structural features of odorants differentially influence their perceived odor. In the olfactory bulb (OB), odorants are represented by ensembles of activated glomeruli. Here we used optical imaging of intrinsic signals to examine how these structural features are represented spatially in the sensory map of the rat OB. We found that the dorsal OB contained two topographically fixed domains; constituent glomeruli in each domain could be activated by odorants with particular functional groups. Within each domain, other structural features such as carbon chain length and branching were represented by local differences in patterns. These results suggest that structural features are categorized into two classes, primary features (functional groups) that characterize each domain, and secondary features that are represented by local positions within each domain. Such hierarchical representations of different structural features correlate well with psychophysical structure-odor relationships.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | MITRAL TUFTED CELLS FUNCTIONAL EXPRESSION 2-DEOXYGLUCOSE UPTAKE HOMOLOGOUS SERIES RECEPTOR RABBIT RAT COMBINATORIAL MOLECULES NEURONS |
| Subjects: | organism description > animal behavior organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organism description > animal behavior > olfactory organs, tissues, organelles, cell types and functions > tissues types and functions > olfactory bulb |
| CSHL Authors: | |
| Communities: | CSHL labs > Mainen lab |
| Depositing User: | Matt Covey |
| Date: | October 2000 |
| Date Deposited: | 29 Jan 2014 15:57 |
| Last Modified: | 29 Jan 2014 15:57 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/29422 |
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