Hippocampal 1H-MRSI in ecstasy users

Obergriesser, T., Ende, G., Braus, D. F., Henn, F. A. (June 2001) Hippocampal 1H-MRSI in ecstasy users. Eur Arch Psychiatry Clin Neurosci, 251 (3). pp. 114-6. ISSN 0940-1334 (Print)0940-1334 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/11697571
DOI: 10.1007/s004060170044


In recent years the illicit drug ecstasy (MDMA, 3,4-methylenedioxymethamphetamine) has come into widespread use among young people. Despite clear evidence for the neurotoxic potential of MDMA in animals, corresponding evidence in humans is limited to indirect findings. In an exploratory study we compared the hippocampal 1H-MRSI (magnetic resonance spectroscopic imaging) spectra of five MDMA users with those of controls with no history of substance abuse. Although 1H

Item Type: Paper
Uncontrolled Keywords: Adult Aspartic Acid/ analogs & derivatives/drug effects Brain Chemistry/drug effects Case-Control Studies Choline Creatine/drug effects Hippocampus/ drug effects/metabolism Humans Magnetic Resonance Spectroscopy N-Methyl-3,4-methylenedioxyamphetamine/ adverse effects Serotonin Agents/ adverse effects Substance-Related Disorders/ diagnosis
Subjects: organs, tissues, organelles, cell types and functions > tissues types and functions > hippocampus
Investigative techniques and equipment > spectroscopy > magnetic resonance spectroscopy
CSHL Authors:
Communities: CSHL labs > Henn lab
Depositing User: Matt Covey
Date: June 2001
Date Deposited: 17 Jan 2014 20:39
Last Modified: 17 Jan 2014 20:39
Related URLs:
URI: https://repository.cshl.edu/id/eprint/29279

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