Gershon, E. S., Kelsoe, J. R., Kendler, K. S., Watson, J. D. (November 2001) A scientific opportunity. Science, 294 (5544). p. 957. ISSN 0036-8075
Abstract
The discovery of susceptibility genes for bipolar disorder and schizophrenia is thought to be one of the most intractable current problems in human genetics. The epidemiological data argue that a substantial portion of the genetic variance seen in these disorders results from a limited number of genes with small effects. This is similar to the situation for many other common diseases with complex inheritance patterns. Nevertheless, recent scientific advances in human genetics, combined with recent findings on bipolar disorder and schizophrenia and the availability of family samples through the U.S. National Institute of Mental Health (NIMH) (www-grb.nimh.nih.gov/gi.html), suggest that a scientific opportunity now exists to identify susceptibility genes for these disorders.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > mental disorders > anxiety disorders diseases & disorders > mental disorders diseases & disorders > mental disorders > mood disorders diseases & disorders > mental disorders > schizophrenia diseases & disorders > mental disorders > mood disorders > depression bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene expression bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function |
| CSHL Authors: | |
| Communities: | CSHL labs |
| Depositing User: | Matt Covey |
| Date: | November 2001 |
| Date Deposited: | 22 Jan 2014 17:53 |
| Last Modified: | 22 Jan 2014 17:53 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/29237 |
Actions (login required)
 |
Administrator's edit/view item |