Osten, P., Margrie, T. W. (June 2013) Mapping brain circuitry with a light microscope. Nat Methods, 10 (6). pp. 515-23. ISSN 1548-7105 (Electronic)1548-7091 (Linking)
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Abstract
The beginning of the 21st century has seen a renaissance in light microscopy and anatomical tract tracing that together are rapidly advancing our understanding of the form and function of neuronal circuits. The introduction of instruments for automated imaging of whole mouse brains, new cell type–specific and trans-synaptic tracers, and computational methods for handling the whole-brain data sets has opened the door to neuroanatomical studies at an unprecedented scale. We present an overview of the present state and future opportunities in charting long-range and local connectivity in the entire mouse brain and in linking brain circuits to function.
| Item Type: | Paper |
|---|---|
| Subjects: | organs, tissues, organelles, cell types and functions > organs types and functions > brain Investigative techniques and equipment > microscopy > flourescence microscopy organs, tissues, organelles, cell types and functions > organs types and functions |
| CSHL Authors: | |
| Communities: | CSHL labs > Osten lab |
| Depositing User: | Matt Covey |
| Date: | June 2013 |
| Date Deposited: | 24 Jun 2013 20:38 |
| Last Modified: | 19 Jul 2021 14:35 |
| PMCID: | PMC3982327 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/28366 |
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