Trotman, L. C., Pandolfi, P. P. (February 2003) PTEN and p53: who will get the upper hand? Cancer Cell, 3 (2). pp. 97-9. ISSN 1535-6108 (Print)1535-6108 (Linking)
Abstract
Mutations of PTEN and p53 are very frequent, yet often mutually exclusive due to functional interdependence of the proteins and, according to a new study, the most intimate possible interaction: direct binding.
Item Type: | Paper |
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Uncontrolled Keywords: | Animals Cell Cycle Genes Tumor Suppressor physiology Humans Mice Mice Knockout PTEN Phosphohydrolase Phosphoric Monoester Hydrolases genetics metabolism Signal Transduction Tumor Suppressor Protein p53 genetics metabolism Tumor Suppressor Proteins genetics metabolism |
Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > PTEN bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > p53 |
CSHL Authors: | |
Communities: | CSHL labs > Trotman lab |
Depositing User: | Brian Soldo |
Date: | February 2003 |
Date Deposited: | 23 Mar 2012 16:07 |
Last Modified: | 08 May 2013 16:47 |
Related URLs: | |
URI: | https://repository.cshl.edu/id/eprint/25523 |
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