Menon, M., Schroeder, J. B., Riske, F. (August 2005) Evaluation of Depth Filtration for the Clarification of Perfusion Mammalian Cell Culture Harvest. In: ACS National Conference 229, San Diego, CA..
Abstract
Depth filtration was found to be an effective option for the clarification of perfusion cell culture harvests containing a glycosylated recombinant protein. This presentation will focus on the effect of process variables and feedstream characteristics on depth filtration performance, recovery, and capacity. The applicability of mathematical models available in literature for process modeling and the operational advantages of depth filtration over tangential flow microfiltration for the clarification of perfusion harvest will also be analyzed.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Uncontrolled Keywords: | Biotechnology depth filtration cell culture clarification diatomaceous earth |
| Subjects: | bioinformatics > quantitative biology biotechnology biotechnology > filtration > depth filtration biotechnology > initial clarification biotechnology > filtration > depth filtration > absolute filtration > tangential flow filtration |
| CSHL Authors: | |
| Depositing User: | CSHL Librarian |
| Date: | 28 August 2005 |
| Date Deposited: | 06 Dec 2011 22:36 |
| Last Modified: | 06 Dec 2011 22:36 |
| URI: | https://repository.cshl.edu/id/eprint/23247 |
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