Huang, Z. J., Di Cristo, G., Ango, F. (September 2007) Development of GABA innervation in the cerebral and cerebellar cortices. Nat Rev Neurosci, 8 (9). pp. 673-686. ISSN 1471-0048
Abstract
In many areas of the vertebrate brain, such as the cerebral and cerebellar cortices, neural circuits rely on inhibition mediated by GABA (gamma-aminobutyric acid) to shape the spatiotemporal patterns of electrical signalling. The richness and subtlety of inhibition are achieved by diverse classes of interneurons that are endowed with distinct physiological properties. In addition, the axons of interneurons display highly characteristic and class-specific geometry and innervation patterns, and thereby distribute their output to discrete spatial domains, cell types and subcellular compartments in neural networks. The cellular and molecular mechanisms that specify and modify inhibitory innervation patterns are only just beginning to be understood.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | GLUTAMIC-ACID DECARBOXYLASE CELL-ADHESION MOLECULES RAT VISUAL-CORTEX INTERNEURON DIVERSITY SERIES ACTION-POTENTIAL INITIATION GAMMA-AMINOBUTYRIC-ACID SYNAPTIC RELEASE SITES BARREL FIELD CORTEX NEUROTROPHIC FACTOR MESSENGER-RNA |
| Subjects: | bioinformatics > genomics and proteomics > small molecules > GABA organs, tissues, organelles, cell types and functions > tissues types and functions > cerebral cortex organism description > animal behavior > visual |
| CSHL Authors: | |
| Communities: | CSHL labs > Huang lab |
| Depositing User: | CSHL Librarian |
| Date: | September 2007 |
| Date Deposited: | 14 Nov 2011 17:32 |
| Last Modified: | 10 Jan 2017 15:52 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/23042 |
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