Vaughn, M. W., Martienssen, R. (September 2005) It's a small RNA world, after all. Science, 309 (5740). pp. 1525-6. ISSN 1095-9203 (Electronic)
Abstract
Small RNAs (sRNAs) can regulate transcript and protein abundance. Previously, they have been identified using traditional cloning approaches, which has limited how many could be characterized. Now, the Meyers and Green laboratories have used massively parallel signature sequencing technology to find over 1.5 million sRNAs in Arabidopsis thaliana. These new sRNAs reveal a greater-than-expected potential role for sRNAs in gene regulation, preferential expression or usage of sRNAs in flowers, and the prospect of targeted sRNA-mediated regulation of pseudogenes. In addition, new plant microRNAs have been identified, some of which may be unique to Arabidopsis.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Arabidopsis genetics metabolism Gene Expression Regulation Plant Genome Plant Genomics MicroRNAs physiology RNA Plant physiology RNA Small Interfering physiology |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > mRNA dynamics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > siRNA |
| CSHL Authors: | |
| Communities: | CSHL labs > Martienssen lab |
| Depositing User: | CSHL Librarian |
| Date: | 2 September 2005 |
| Date Deposited: | 05 Jan 2012 16:10 |
| Last Modified: | 09 Apr 2014 20:49 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/22726 |
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