Martienssen, R. A., Zaratiegui, M., Goto, D. B. (August 2005) RNA interference and heterochromatin in the fission yeast Schizosaccharomyces pombe. Trends Genet, 21 (8). pp. 450-6. ISSN 0168-9525 (Print)
Abstract
Fission yeast is a useful model for RNA interference because it has single-copy genes for components of the RNAi pathway such as argonaute, dicer and RNA-dependent RNA polymerase (RdRP). Functions for RNAi revealed in S. pombe, such as heterochromatic silencing and chromosome segregation, are likely to be ancient because they are shared with some other eukaryotes. The underlying mechanisms are being rapidly unraveled.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Cell Division Centromere genetics metabolism DNA Transposable Elements genetics Gene Silencing Heterochromatin genetics metabolism Histones metabolism Models Genetic Polynucleotide Adenylyltransferase metabolism RNA Interference RNA Replicase metabolism RNA-Directed DNA Polymerase metabolism Schizosaccharomyces cytology genetics metabolism |
| Subjects: | bioinformatics > genomics and proteomics > annotation > map annotation bioinformatics > genomics and proteomics > Mapping and Rendering bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi organism description > yeast > Saccharomyces |
| CSHL Authors: | |
| Communities: | CSHL labs > Martienssen lab |
| Depositing User: | CSHL Librarian |
| Date: | August 2005 |
| Date Deposited: | 09 Jan 2012 15:44 |
| Last Modified: | 09 Apr 2014 20:58 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/22648 |
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