Sachidanandam, R. (September 2004) RNAi: design and analysis. Curr Protoc Bioinformatics, Chapte. Unit 12.3. ISSN 1934-340X (Electronic)
Abstract
RNAi is a novel genetic tool that is poised to revolutionize the study of genetics and gene networks. Use of this tool requires knowledge of the underlying mechanisms and application of this knowledge to the construction of a gene-silencing library. This unit discusses approaches to rational design of this library and its use in experiments. It focuses on the design algorithms developed so far and briefly discuss several issues that could lead to improvements in the current design algorithms.
| Item Type: | Paper |
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| Additional Information: | |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene silencing |
| CSHL Authors: | |
| Depositing User: | CSHL Librarian |
| Date: | September 2004 |
| Date Deposited: | 25 Jan 2012 19:17 |
| Last Modified: | 25 Jan 2012 19:17 |
| URI: | https://repository.cshl.edu/id/eprint/22470 |
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