Hannon, G. J., Rossi, J. J. (September 2004) Unlocking the potential of the human genome with RNA interference. Nature, 431 (7006). pp. 371-8. ISSN 1476-4687 (Electronic)
DOI: 10.1038/nature02870
Abstract
The discovery of RNA interference (RNAi) may well be one of the transforming events in biology in the past decade. RNAi can result in gene silencing or even in the expulsion of sequences from the genome. Harnessed as an experimental tool, RNAi has revolutionized approaches to decoding gene function. It also has the potential to be exploited therapeutically, and clinical trials to test this possibility are already being planned.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Drug Evaluation Preclinical/methods Gene Therapy methods Genome Human Genomics methods Humans RNA Interference RNA Small Interfering genetics metabolism |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi |
| CSHL Authors: | |
| Communities: | CSHL labs > Hannon lab |
| Depositing User: | CSHL Librarian |
| Date: | 16 September 2004 |
| Date Deposited: | 09 Feb 2012 15:31 |
| Last Modified: | 02 Dec 2016 19:57 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/22380 |
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