Chitwood, D. H., Timmermans, M. C. P. (September 2010) Small RNAs are on the move. Nature, 467 (7314). pp. 415-419. ISSN 0028-0836
Abstract
A key feature of RNA interference is its ability to spread from cell to cell. Such non-cell-autonomous gene silencing has been characterized extensively in both plants and animals, but the identity of the mobile silencing signal has remained elusive. Several recent studies now shed light on the identity of this signal in plants, and indicate that small RNA molecules-from short-interfering RNAs to microRNAs-are capable of moving between cells and through the vasculature. The movement of small, 21-24-nucleotide RNA species has implications for biological processes ranging from developmental patterning and stress responses to epigenetic inheritance.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | SILENCING SIGNAL ARABIDOPSIS GENE INTERFERENCE MICRORNAS CELLS PATHWAYS SIRNAS PLANTS VIRUS |
| Subjects: | organism description > plant > Arabidopsis bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi organism description > plant bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > shRNA organism description > virus |
| CSHL Authors: | |
| Communities: | CSHL labs > Timmermans lab School of Biological Sciences > Publications |
| Depositing User: | CSHL Librarian |
| Date: | 23 September 2010 |
| Date Deposited: | 28 Sep 2011 15:02 |
| Last Modified: | 26 Sep 2014 19:41 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/15387 |
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