Items where Subject is "Investigative techniques and equipment > x ray crystallography"

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Number of items at this level: 68.

A

Auster, A. S., Joshua-Tor, L. (2004) The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding. J Biol Chem, 279 (5). pp. 3733-42. ISSN 0021-9258 (Print)

B

Balendiran, K., Bonventre, J., Knott, R., Jack, W., Benner, J., Schildkraut, I., Anderson, J. E. (1994) Expression, purification, and crystallization of restriction endonuclease PvuII with DNA containing its recognition site. Proteins, 19 (1). pp. 77-9. ISSN 0887-3585 (Print)

Barford, D., Flint, A. J., Tonks, N. K. (1994) Crystal structure of human protein tyrosine phosphatase 1B. Science, 263 (5152). pp. 1397-1404.

Barford, D., Keller, J. C. (1994) Co-crystallization of the catalytic subunit of the serine/threonine specific protein phosphatase 1 from human in complex with microcystin LR. J Mol Biol, 235 (2). pp. 763-6. ISSN 0022-2836 (Print)

Barford, D., Keller, J. C., Flint, A. J., Tonks, N. K. (1994) Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli. Journal of Molecular Biology, 239 (5). pp. 726-730. ISSN 0022-2836

Blake, P. R., Day, M. W., Hsu, B. T., Joshua-Tor, L., Park, J. B., Hare, D. R., Adams, M. W., Rees, D. C., Summers, M. F. (1992) Comparison of the X-ray structure of native rubredoxin from Pyrococcus furiosus with the NMR structure of the zinc-substituted protein. Protein Sci, 1 (11). pp. 1522-5. ISSN 0961-8368 (Print)0961-8368 (Linking)

C

Carmel, G., Leichus, B., Cheng, X., Patterson, S. D., Mirza, U., Chait, B. T., Kuret, J. (1994) Expression, purification, crystallization, and preliminary x-ray analysis of casein kinase-1 from Schizosaccharomyces pombe. J Biol Chem, 269 (10). pp. 7304-9. ISSN 0021-9258 (Print)

Cheng, X., Balendiran, K., Schildkraut, I., Anderson, J. E. (1995) Crystal structure of the PvuII restriction endonuclease. Gene, 157 (1-2). pp. 139-40. ISSN 0378-1119 (Print)

Cheng, X., Balendiran, K., Schildkraut, I., Anderson, J. E. (1994) Structure of PvuII endonuclease with cognate DNA. Embo J, 13 (17). pp. 3927-35. ISSN 0261-4189 (Print)

D

Day, M. W., Hsu, B. T., Joshua-Tor, L., Park, J. B., Zhou, Z. H., Adams, M. W. W., Rees, D. C. (1992) X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus. Protein Science, 1 (11). pp. 1494-1507. ISSN 09618368 (ISSN)

Ding, J. Z., Hayashi, M. K., Zhang, Y., Manche, L., Krainer, A. R., Xu, R. M. (1999) Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA. Genes & Development, 13 (9). pp. 1102-1115. ISSN 0890-9369

E

Elkayam, E., Parmar, R., Brown, C. R., Willoughby, J. L., Theile, C. S., Manoharan, M., Joshua-Tor, L. (2017) siRNA carrying an (E)-vinylphosphonate moiety at the 5' end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2. Nucleic Acids Res, 45 (6). pp. 3528-3536. ISSN 1362-4962 (Electronic)0305-1048 (Linking)

Enemark, E. J., Chen, G., Vaughn, D. E., Stenlund, A., Joshua-Tor, L. (2000) Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus. Molecular Cell, 6 (1). pp. 149-158. ISSN 1097-2765

Enemark, E. J., Joshua-Tor, L. (2006) Mechanism of DNA translocation in a replicative hexameric helicase. Nature, 442 (7100). pp. 270-275. ISSN 1476-4687 (Electronic)

Enemark, E. J., Stenlund, A., Joshua-Tor, L. (2002) Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex. Embo Journal, 21 (6). pp. 1487-1496. ISSN 0261-4189

F

Faehnle, C. R., Walleshauser, J., Joshua-Tor, L. (2014) Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. Nature, 514 (7521). pp. 252-6. ISSN 0028-0836

G

Gillitzer, E., Chen, G., Stenlund, A. (2000) Separate domains in E1 and E2 proteins serve architectural and productive roles for cooperative DNA binding. Embo Journal, 19 (12). pp. 3069-3079. ISSN 0261-4189

H

Hoffmann, K. M. V., Tonks, N. K., Barford, D. (1997) The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu. Journal of Biological Chemistry, 272 (44). pp. 27505-27508. ISSN 0021-9258

Hsu, H. C., Stillman, B., Xu, R. M. (2005) Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing. Proc Natl Acad Sci U S A, 102 (24). pp. 8519-24. ISSN 0027-8424 (Print)

Hu, G., Lin, G., Wang, M., Dick, L., Xu, R. M., Nathan, C., Li, H. (2006) Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate. Molecular Microbiology, 59 (5). pp. 1417-1428. ISSN 0950382X

J

Jasti, J., Furukawa, H., Gonzales, E. B., Gouaux, E. (2007) Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature, 449 (7160). pp. 316-23. ISSN 1476-4687 (Electronic) 1476-4687 (Linking)

Jiang, J., Zhang, Y., Krainer, A. R., Xu, R. M. (1999) Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein. Proceedings of the National Academy of Sciences of the United States of America, 96 (7). pp. 3572-7. ISSN 0027-8424 (Print)0027-8424

Joshua-Tor, L., Rabinovich, D., Hope, H., Frolow, F., Appella, E., Sussman, J. L. (1988) The three-dimensional structure of a DNA duplex containing looped-out bases. Nature, 334 (6177). pp. 82-4. ISSN 0028-0836 (Print)0028-0836 (Linking)

Joshua-Tor, L., Sussman, J. L. (1993) The Coming of Age of DNA Crystallography. Current Opinion in Structural Biology, 3 (3). pp. 323-335. ISSN 0959-440X

Joshua-Tor, L., Xu, H., Johnston, S., Rees, D. (1995) Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269 (5226). pp. 945-950. ISSN 0036-80751095-9203

K

Karakas, E., Simorowski, N., Furukawa, H. (2009) Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. Embo Journal, 28 (24). pp. 3910-3920. ISSN 0261-4189

Klemm, J. D., Rould, M. A., Aurora, R., Herr, W., Pabo, C. O. (1994) Crystal-Structure of the Oct-1 Pou Domain Bound to an Octamer Site - DNA Recognition with Tethered DNA-Binding Modules. Cell, 77 (1). pp. 21-32. ISSN 0092-8674

Klimasauskas, S., Kumar, S., Roberts, R. J., Cheng, X. D. (1994) Hhal Methyltransferase Flips Its Target Base out of the DNA Helix. Cell, 76 (2). pp. 357-369. ISSN 0092-8674

Kumar, P. R., Yu, Y., Sternglanz, R., Johnston, S. A., Joshua-Tor, L. (2008) NADP regulates the yeast GAL induction system. Science, 319 (5866). pp. 1090-2. ISSN 1095-9203 (Electronic)

Kumar, S., Cheng, X., Pflugrath, J. W., Roberts, R. J. (1992) Purification, crystallization, and preliminary X-ray diffraction analysis of an M.HhaI-AdoMet complex. Biochemistry, 31 (36). pp. 8648-53. ISSN 0006-2960 (Print)0006-2960 (Linking)

Kuret, J., Pflugrath, J. W. (1991) Crystallization and preliminary X-ray analysis of the cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae. Biochemistry, 30 (43). pp. 10595-600. ISSN 0006-2960 (Print)0006-2960 (Linking)

L

Lavy, T., Kumar, P. R., He, H. Z., Joshua-Tor, L. (2012) The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes & Development, 26 (3). pp. 294-303. ISSN 0890-9369

Lee, K., Sharma, R., Shrestha, O. K., Bingman, C. A., Craig, E. A. (2016) Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits. Nat Struct Mol Biol, 23 (11). pp. 1003-1010. ISSN 1545-9993 (Print)1545-9985 (Linking)

Lee, Y. H., Lin, K., Okar, D., Alfano, N. L., Sarma, R., Pflugrath, J. W., Pilkis, S. J. (1994) Preliminary-X-Ray Analysis of a Truncated Form of Recombinant Fructose-2,6-Bisphosphatase. Journal of Molecular Biology, 235 (3). pp. 1147-1151. ISSN 0022-2836

Liu, Y., Gong, W., Huang, C. C., Herr, W., Cheng, X. (1999) Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16. Genes and Development, 13 (13). pp. 1692-703. ISSN 0890-9369 (Print)

M

Messick, T. E., Chmiel, N. H., Golinelli, M. P., Langer, M. R., Joshua-Tor, L., David, S. S. (2002) Noncysteinyl coordination to the [4Fe-4S](2+) cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster. Biochemistry, 41 (12). pp. 3931-3942. ISSN 0006-2960

Min, J. R., Landry, J., Sternglanz, R., Xu, R. M. (2001) Crystal structure of a SIR2 homolog-NAD complex. Cell, 105 (2). pp. 269-279. ISSN 0092-8674

N

Neel, B. G., Tonks, N. K. (1997) Protein tyrosine phosphatases in signal transduction. Current Opinion in Cell Biology, 9 (2). pp. 193-204. ISSN 0955-0674

O

O'Farrell, P. A., Gonzalez, F., Zheng, W., Johnston, S. A., Joshua-Tor, L. (1999) Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure, 7 (6). pp. 619-27. ISSN 0969-2126

O'Farrell, P. A., Joshua-Tor, L. (2007) Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure. Biochem J, 401 (2). pp. 421-8. ISSN 0264-6021

O'Gara, M., Klimasauskas, S., Roberts, R. J., Cheng, X. (1996) Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. Journal of Molecular Biology, 261 (5). pp. 634-45. ISSN 0022-2836 (Print)

O'Gara, M., McCloy, K., Malone, T., Cheng, X. (1995) Structure-based sequence alignment of three AdoMet-dependent DNA methyltransferases. Gene, 157 (1-2). pp. 135-8. ISSN 0378-1119 (Print)

O'Gara, M., Roberts, R. J., Cheng, X. (1996) A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase. Journal of Molecular Biology, 263 (4). pp. 597-606. ISSN 0022-2836 (Print)

P

Pannifer, A. D. B., Flint, A. J., Tonks, N. K., Barford, D. (1998) Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by X-ray crystallography. Journal of Biological Chemistry, 273 (17). pp. 10454-10462. ISSN 0021-9258

R

Rees, D. C., Kim, J., Georgiadis, M. M., Komiya, H., Chirino, A. J., Woo, D., Schlessman, J., Chan, M. K., Joshua-Tor, L., Santillan, G., Chakrabarti, P., Hsu, B. T. (1993) Crystal Structures of the Iron Protein and Molybdenum-Iron Protein of Nitrogenase. In: Molybdenum Enzymes, Cofactors, and Model Systems. ACS Symposium Series, 535 (535). American Chemical Society, pp. 170-185. ISBN 0-8412-2708-X

Romero-Hernandez, Annabel, Simorowski, Noriko, Karakas, Erkan, Furukawa, Hiro (2016) Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain. Neuron, 92 (6). pp. 1324-1336. ISSN 0896-6273

Russell, S. J., Gonzalez, F., Joshua-Tor, L., Johnston, S. A. (2001) Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases. Chemistry & Biology, 8 (10). pp. 941-950. ISSN 1074-5521

S

Schalch, T., Job, G., Noffsinger, V. J., Shanker, S., Kuscu, C., Joshua-Tor, L., Partridge, J. F. (2009) High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin. Mol Cell, 34 (1). pp. 36-46. ISSN 1097-4164 (Electronic)

Schalch, T., Job, G., Shanker, S., Partridge, J. F., Joshua-Tor, L. (2011) The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nature Structural and Molecular Biology, 18 (12). pp. 1351-1357. ISSN 15459993 (ISSN)

Schlessman, J. L., Woo, D., Joshua-Tor, L., Howard, J. B., Rees, D. C. (1998) Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum. Journal of Molecular Biology, 280 (4). pp. 669-685. ISSN 00222836 (ISSN)

Song, J. J., Liu, J., Tolia, N. H., Schneiderman, J., Smith, S. K., Martienssen, R. A., Hannon, G. J., Joshua-Tor, L. (2003) The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol, 10 (12). pp. 1026-32. ISSN 1072-8368 (Print)

Strauss, M. G., Westbrook, E. M., Naday, I., Coleman, T. A., Westbrook, M. L., Travis, D. J., Sweet, R. M., Pflugrath, J. W., Stanton, M. (1990) Ccd-Based Detector for Protein Crystallography with Synchrotron X-Rays. Nuclear Instruments & Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment, 297 (1-2). pp. 275-295. ISSN 0168-9002

Sussman, J. L., Joshua-Tor, L., Hirshberg, M., Saper, M. A. , Frowlow, F. , Hope, H., Appella, E. (1988) A Kinked Model of a DNA Tridecamer with an Unpaired Adenosine: Energy Minimization and X-ray Structural Studies. In: Molecular Structure: Chemical Reactivity and Biological Activity. Oxford University Press, pp. 195-200.

T

Tajima, N., Karakas, E., Grant, T., Simorowski, N., Diaz-Avalos, R., Grigorieff, N., Furukawa, H. (2016) Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature, 534 (7605). pp. 63-8. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Takahashi, H., Shin, Y., Cho, S. J., Zago, W. M., Nakamura, T., Gu, Z., Ma, Y., Furukawa, H., Liddington, R., Zhang, D., Tong, G., Chen, H. S., Lipton, S. A. (2007) Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif. Neuron, 53 (1). pp. 53-64. ISSN 0896-6273 (Print)0896-6273 (Linking)

Tocilj, A., On, K. F., Yuan, Z., Sun, J., Elkayam, E., Li, H., Stillman, B., Joshua-Tor, L. (2017) Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6. ISSN 2050-084X (Electronic)2050-084X (Linking)

Tolia, N. H., Enemark, E. J., Sim, B. K., Joshua-Tor, L. (2005) Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. Cell, 122 (2). pp. 183-93. ISSN 0092-8674 (Print)

V

Van Aalten, D. M. F., Crielaard, W., Hellingwerf, K. J., Joshua-Tor, L. (2000) Conformational substates in different crystal forms of the photoactive yellow protein - Correlation with theoretical and experimental flexibility. Protein Science, 9 (1). pp. 64-72. ISSN 0961-8368

Van Aalten, D. M. F., Crielaard, W., Hellingwerf, K. J., Joshua-Tor, L. (2002) Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 Å resolution. Acta Crystallographica Section D: Biological Crystallography, 58 (4). pp. 585-590. ISSN 09074449 (ISSN)

Vasquez, V., Cortes, D. M., Furukawa, H., Perozo, E. (2007) An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis. Biochemistry, 46 (23). pp. 6766-73. ISSN 0006-2960 (Print)0006-2960 (Linking)

van Aalten, D. M., Erlanson, D. A., Verdine, G. L., Joshua-Tor, L. (1999) A structural snapshot of base-pair opening in DNA. Proc Natl Acad Sci U S A, 96 (21). pp. 11809-14. ISSN 0027-8424 (Print)

van Aalten, D. M., Haker, A., Hendriks, J., Hellingwerf, K. J., Joshua-Tor, L., Crielaard, W. (2002) Engineering photocycle dynamics. Crystal structures and kinetics of three photoactive yellow protein hinge-bending mutants. J Biol Chem, 277 (8). pp. 6463-8. ISSN 0021-9258 (Print)

van Aalten, D. M. F., Chong, C. R., Joshua-Tor, L. (2000) Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes. Biochemistry, 39 (33). pp. 10082-10089. ISSN 0006-2960

X

Xu, R. M., Carmel, G., Kuret, J., Cheng, X. (1996) Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 93 (13). pp. 6308-13. ISSN 0027-8424

Xu, R. M., Jokhan, L., Cheng, X., Mayeda, A., Krainer, A. R. (1997) Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs. Structure, 5 (4). pp. 559-70. ISSN 0969-2126 (Print)0969-2126

Xu, R. M., Koch, C., Liu, Y., Horton, J. R., Knapp, D., Nasmyth, K., Cheng, X. (1997) Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis. Structure, 5 (3). pp. 349-58. ISSN 0969-2126 (Print)

Y

Yang, J., Dokurno, P., Tonks, N. K., Barford, D. (2001) Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion. Embo Journal, 20 (14). pp. 3645-3656. ISSN 0261-4189

Z

Zheng, W., Johnston, S. A., Joshua-Tor, L. (1998) The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell, 93 (1). pp. 103-9. ISSN 0092-8674 (Print)0092-8674 (Linking)

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