Items where Subject is "cancer organoids"

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Number of items at this level: 40.

A

Abulwerdi, F. A., Xu, W., Ageeli, A. A., Yonkunas, M. J., Arun, G., Nam, H., Schneekloth, J. S., Dayie, T. K., Spector, D., Baird, N., Le Grice, S. F. J. (February 2019) Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1. ACS Chemical Biology, 14 (2). pp. 223-235. ISSN 15548929 (ISSN) (Public Dataset)

B

Baker, L. A., Tiriac, H., Tuveson, D. A. (2019) Generation and Culture of Human Pancreatic Ductal Adenocarcinoma Organoids from Resected Tumor Specimens. Methods Mol Biol, 1882. pp. 97-115. ISSN 1064-3745

Baker, L. A., Tuveson, D. A. (2019) Generation and Culture of Tumor and Metastatic Organoids from Murine Models of Pancreatic Ductal Adenocarcinoma. Methods Mol Biol, 1882. pp. 117-133. ISSN 1064-3745

Beyaz, S., Mana, M. D., Roper, J., Kedrin, D., Saadatpour, A., Hong, S. J., Bauer-Rowe, K. E., Xifaras, M. E., Akkad, A., Arias, E., Pinello, L., Katz, Y., Shinagare, S., Abu-Remaileh, M., Mihaylova, M. M., Lamming, D. W., Dogum, R., Guo, G., Bell, G. W., Selig, M., Nielsen, G. P., Gupta, N., Ferrone, C. R., Deshpande, V., Yuan, G. C., Orkin, S. H., Sabatini, D. M., Yilmaz, O. H. (March 2016) High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature, 531 (7592). pp. 53-8. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Beyaz, S., Roper, J., Bauer-Rowe, K. E., Xifaras, M. E., Ergin, I., Dohnalova, L., Biton, M., Shekar, K., Mou, H. W., Eskiocak, O., Ozata, D., Papciak, K., Chung, C., Almeqdadi, M., Fein, M., Valle-Encinas, E., Erdemir, A., Dogum, K, Garipcan, A., Meyer, H., Fox, J.G., Elinav, E., Kucukural, A., Kumar, P., McAleer, J., Thaiss, C.A., Regev, A., Orkin, S. H., Yilmaz, O. H. (September 2020) Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis. BioRxiv. (Unpublished)

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter A, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Rishi, Arvind, Wilkinson, John Erby, McCombie, William Richard, Kostroff, Karen, Spector, David L (August 2021) Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics. BioRxiv.

Burkhart, R. A., Baker, L. A., Tiriac, H. (May 2018) Testing Susceptibility of Patient-Derived Organoid Cultures to Therapies: Pharmacotyping. Methods Mol Biol, 1787. pp. 253-261. ISSN 1064-3745

Buscaglia, Jonathan M., Bucobo, Juan Carlos, Tiriac, Herve, Tzimas, Demetrios, Grewal, Suman, LaComb, Joseph, Rowehl, Leahana, Nagula, Satish, Wu, Maoxin, Kim, Joseph, Sasson, Aaron, Li, Ellen, Young, Candice M., Tuveson, David A. (May 2017) 111 Successful Creation of Pancreatic Cancer Organoids By Means of Eus-Guided Fine-Needle Biopsy (EUS-FNB) for Personalized Cancer Treatment. Gastrointestinal Endoscopy, 85 (5, Sup). AB50-AB51. ISSN 0016-5107

C

Chan, K., Robert, F., Oertlin, C., Kapeller-Libermann, D., Avizonis, D., Gutierrez, J., Handly-Santana, A., Doubrovin, M., Park, J., Schoepfer, C., Da Silva, B., Yao, M., Gorton, F., Shi, J., Thomas, C. J., Brown, L. E., Porco, J. A., Pollak, M., Larsson, O., Pelletier, J., Chio, I. I. C. (November 2019) eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma. Nat Commun, 10 (1). p. 5151. ISSN 2041-1723

Ciccone, M. F., Trousdell, M. C., Dos Santos, C. O. (November 2020) Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells. J Mammary Gland Biol Neoplasia, 25 (4). pp. 351-366. ISSN 1083-3021

Clevers, Hans, Tuveson, David A (2019) Organoid Models for Cancer Research. In: ANNUAL REVIEW OF CANCER BIOLOGY, VOL 3. Annual Reviews, pp. 223-234.

D

Dreyer, Stephan B, Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc, Moran-Jones, Kim, Wright, Derek W, Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J, McGregor, Grant A, Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L, Candido, Juliana, Balkwill, Frances, Barry, Simon T, Grützmann, Robert, Rahib, Lola, Glasgow Precision Oncology Laboratory,, , Australian Pancreatic Cancer Genome Initiative, , Johns, Amber, Pajic, Marina, Froeling, Fieke EM, Beer, Phillip, Musgrove, Elizabeth A, Petersen, Gloria M, Ashworth, Alan, Frame, Margaret C, Crawford, Howard C, Simeone, Diane M, Lord, Chris, Mukhopadhyay, Debabrata, Pilarsky, Christian, Tuveson, David A, Cooke, Susanna L, Jamieson, Nigel B, Morton, Jennifer P, Sansom, Owen J, Bailey, Peter J, Biankin, Andrew V, Chang, David K (January 2021) Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer. Gastroenterology, 160 (1). 362-377.e13. ISSN 0016-5085

Driehuis, E., Kolders, S., Spelier, S., Lohmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., Van Es, J. H., Geurts, V., He, G. W., van Jaarsveld, R. H., Oka, R., Muraro, M. J., Vivie, J., Zandvliet, Mmjm, Hendrickx, A. P. A., Iakobachvili, N., Sridevi, P., Kranenburg, O., van Boxtel, R., Kops, Gjpl, Tuveson, D. A., Peters, P. J., van Oudenaarden, A., Clevers, H. (May 2019) Oral mucosal organoids as a potential platform for personalized cancer therapy. Cancer Discov, 9 (7). pp. 852-871. ISSN 2159-8274

E

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Da Silva, B., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grutzmann, R., Aust, D., Gimotty, P. A., Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A., Tuveson, D. A. (June 2019) The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. Science, 364 (6446). pp. 1156-1162. ISSN 0036-8075

F

Feigin, M. E., Tuveson, D. A. (April 2017) Organoid models to interrogate GPCR regulation of pancreatic tumorigenesis. Faseb Journal, 31 (Supple). Meeting Abstract: lb524 . ISSN 0892-6638

Froeling, Fieke E.M., Plenker, Dennis, O’Kane, Grainne, Aguirre, Andrew J., Wolpin, Brian M., Laheru, Daniel A., Saif, M Wasif, Yu, Kenneth H., Fischer, Sandra, Gallinger, Steven, Knox, Jennifer J., Jaffee, Elizabeth M., Tuveson, David A. (September 2020) Organoid Personalized Therapeutics and the Pancreatic Adenocarcinoma Signature Stratification for treatment (PASS) – 01 trial. In: The London Pancreas Workshop 2020.

G

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall E, Tuveson, David A, Tsai, Susan, Haab, Brian B (January 2021) Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA. Clinical Cancer Research, 27 (1). pp. 226-236. ISSN 1078-0432

H

Hou, Shurong, Tiriac, Hervé, Sridharan, Banu Priya, Scampavia, Louis, Madoux, Franck, Seldin, Jan, Souza, Glauco R, Watson, Donald, Tuveson, David, Spicer, Timothy P (July 2018) Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. Slas Discovery, 23 (6). pp. 574-584. ISSN 2472-5552

Hwang, Chang-il, Roe, Jae-Seok, Lee, Eun Jung, Tonelli, Claudia, Somervile, Tim DD, Yao, Melissa, Milazzo, Joseph P, Tiriac, Herve, Park, Youngkyu, Vakoc, Christopher, Tuveson, David (December 2019) Engrailed-1 promotes pancreatic cancer progression via antagonizing COMPASS activity. In: AACR Special Conference on Pancreatic Cancer - Advances in Science and Clinical Care.

L

Lau, A. N., Li, Z., Danai, L. V., Westermark, A. M., Darnell, A. M., Ferreira, R., Gocheva, V., Sivanand, S., Lien, E. C., Sapp, K. M., Mayers, J. R., Biffi, G., Chin, C. R., Davidson, S. M., Tuveson, D. A., Jacks, T., Matheson, N. J., Yilmaz, O., Vander Heiden, M. G. (July 2020) Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma. Elife, 9. ISSN 2050-084x

Lyons, Scott K, Plenker, Dennis, Trotman, Lloyd C (July 2021) Advances in preclinical evaluation of experimental antibody-drug conjugates. Cancer Drug Resistance, 4. pp. 745-754. ISSN 2578-532X

M

Miyabayashi, K., Tuveson, D. A., Yu, K. H. (2018) Multiparameter modalities for the study of patients in the setting of individualized medicine. In: Pancreatic Cancer. Springer Nature, pp. 1523-1549. ISBN 9781493971930 (ISBN); 9781493971916 (ISBN)

Munoz-Sagastibelza, M., Tiriac, H., Vignesh, S., Sanchez, J. P., Somma, J., Li, E., Bucobo, J. C., Tzimas, D. J., Wu, M., Martello-Rooney, L., Tuveson, D., Buscaglia, J. (July 2018) Living biobank of endoscopic ultrasound guided fine needle biopsy-derived PDAC organoids: A study of two contrasting populations. Cancer Epidemiology Biomarkers & Prevention, 27 (7 Supp). p. 95. ISSN 1055-9965

N

Nizam, Aaron, Chung, Charlie, Goldberg, Gary L, Beyaz, Semir (July 2021) Abstract LB236: Utilizing endometrial tumor organoids to model cancer immunomodulation. In: AACR Annual Meeting 2021.

Nizam, Aaron, Chung, Charlie, Goldberg, Gary L, Beyaz, Semir (July 2021) Utilizing endometrial tumor organoids to model cancer immunomodulation. In: AACR Annual Meeting 2021.

O

Oni, Tobiloba E, Bautista, Carmelita, Merrill, Joseph R, Goos, Jeroen ACM, Rivera, Keith D, Miyabayashi, Koji, Biffi, Giulia, Garcia, Libia, Plenker, Dennis, Patel, Hardik, Elyada, Ela, Samaritano, Maria, Yu, Kenneth H, Pappin, Darryl J, Goggins, Michael G, Hruban, Ralph H, Lewis, Jason S, Lyons, Scott K, Yeh, Johannes T, Tuveson, David A (September 2020) Detection of incipient pancreatic cancer with novel tumor-specific antibodies in mouse models. BioRxiv. (Unpublished)

P

Park, S., Brugiolo, M., Akerman, M., Das, S., Urbanski, L., Geier, A., Kesarwani, A. K., Fan, M., Leclair, N., Lin, K. T., Hu, L., Hua, I., George, J., Muthuswamy, S. K., Krainer, A. R., Anczukow, O. (November 2019) Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis. Cell Rep, 29 (9). 2672-2688.e7. ISSN 2211-1247 (Public Dataset)

Ponz-Sarvise, M., Corbo, V., Tiriac, H., Engle, D. D., Frese, K. K., Oni, T. E., Hwang, C. I., Ohlund, D., Chio, I. I. C., Baker, L. A., Filippini, D., Wright, K., Bapiro, T. E., Huang, P. S., Smith, P. D., Yu, K. H., Jodrell, D. I., Park, Y., Tuveson, D. A. (September 2019) Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer. Clin Cancer Res, 25 (22). pp. 6742-6755. ISSN 1078-0432 (Print)1078-0432

R

Roper, J., Tammela, T., Cetinbas, N. M., Akkad, A., Roghanian, A., Rickelt, S., Almeqdadi, M., Wu, K., Oberli, M. A., Sanchez-Rivera, F., Park, Y. K., Liang, X., Eng, G., Taylor, M. S., Azimi, R., Kedrin, D., Neupane, R., Beyaz, S., Sicinska, E. T., Suarez, Y., Yoo, J., Chen, L., Zukerberg, L., Katajisto, P., Deshpande, V., Bass, A. J., Tsichlis, P. N., Lees, J., Langer, R., Hynes, R. O., Chen, J., Bhutkar, A., Jacks, T., Yilmaz, O. H. (June 2017) In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol, 35 (6). pp. 569-576. ISSN 1546-1696 (Electronic)1087-0156 (Linking)

Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye Malli, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Wu, Katherine, Oberli, Matthias, Sanchez-Rivera, Francisco, Park, Yoona, Liang, Xu, Eng, George, Taylor, Martin S, Azimi, Roxana, Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Sicinska, Ewa T, Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam, Tsichlis, Philip N, Lees, Jacqueline, Langer, Robert, Hynes, Richard O, Chen, Jianzhu, Bhutkar, Arjun J, Jacks, Tyler, Yilmaz, Omer H (May 2018) In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. In: AACR Special Conference on Advances in Modeling Cancer in Mice - Technology, Biology, and Beyond.

S

Seppala, Toni T, Zimmerman, Jacquelyn W, Rozich, Noah, Blair, Alex, Javed, Ammar, Cameron, John L, Burns, William R, He, Jin, Tuveson, David, Wolfgang, Christopher L, Ryan, David P, Kimmelman, Alec, Herman, Joseph M, Messersmith, Wells, Hong, Theodore S, Ting, David T, Burkhart, Richard Andrew (August 2020) Patient-derived organoids may facilitate precision medicine in pancreatic cancer: Demonstrating feasibility in the context of a multi-center clinical trial. In: AACR Annual Meeting.

Seppälä, Toni T, Zimmerman, Jacquelyn W, Sereni, Elisabetta, Plenker, Dennis, Suri, Reecha, Rozich, Noah, Blair, Alex, Thomas, Dwayne L, Teinor, Jonathan, Javed, Ammar, Patel, Hardik, Cameron, John L, Burns, William R, He, Jin, Tuveson, David A, Jaffee, Elizabeth M, Eshleman, James, Szabolcs, Annamaria, Ryan, David P, Ting, David T, Wolfgang, Christopher L, Burkhart, Richard A (September 2020) Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. Annals of Surgery, 272 (3). pp. 427-435. ISSN 0003-4932

T

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschenes, A., Somerville, T., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., LaComb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. A., Johnson, M., Arora, K., Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E. D., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P. J., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O'Kane, G. M., Notta, F., Kim, E. J., Crawford, J. M., Devoe, C. E., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R. A., Knox, J. J., Krasnitz, A., Gallinger, S., Tuveson, D. A. (May 2018) Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery, 8 (9). pp. 1112-1129. ISSN 21598274 (Public Dataset)

Tiriac, H., Bucobo, J. C., Tzimas, D., Grewel, S., Lacomb, J. F., Rowehl, L. M., Nagula, S., Wu, M., Kim, J., Sasson, A., Vignesh, S., Martello, L., Munoz-Sagastibelza, M., Somma, J., Tuveson, D. A., Li, E., Buscaglia, J. M. (June 2018) Successful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized cancer treatment. Gastrointest Endosc, 87 (6). pp. 1474-1480. ISSN 0016-5107

Tiriac, H., Burkhart, R. A., Belleau, P., Young, M. C., Ma, M., Engle, D. D., Li, E., Yu, K. H., Tuveson, D. A. (May 2018) Pharmacotyping patients using pancreatic cancer organoids. Cancer Research, 78 (10, Su). ISSN 0008-5472

Tiriac, H., Plenker, D., Baker, L. A., Tuveson, D. A. (March 2019) Organoid models for translational pancreatic cancer research. Curr Opin Genet Dev, 54. pp. 7-11. ISSN 0959-437x

Truong, Thu H, Benner, Elizabeth A, Hagen, Kyla M, Temiz, Nuri A, Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Trousdell, Marygrace C, Pengo, Thomas, Guillen, Katrin P, Welm, Bryan E, Dos Santos, Camila O, Telang, Sucheta, Lange, Carol A, Ostrander, Julie H (June 2021) PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer. Oncogene. ISSN 0950-9232

Tuveson, D., Clevers, H. (June 2019) Cancer modeling meets human organoid technology. Science, 364 (6444). pp. 952-955. ISSN 0036-8075

Tuveson, David A (April 2021) Fighting the Sixth Decade of the Cancer War with Better Cancer Models. Cancer Discovery, 11 (4). pp. 801-804. ISSN 2159-8274

Y

Yordanov, Georgi Nenov (July 2019) Myc and Spdef: two transcription factors hijacked by pancreatic cancer. PhD thesis, Cold Spring Harbor.

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