Items where Subject is "bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > PTEN"

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Authors | Item Type
Jump to: A | B | C | F | H | I | J | L | M | N | P | S | T | W | X | Y | Z
Number of items at this level: 45.

A

Alimonti, A., Nardella, C., Chen, Z., Clohessy, J. G., Carracedo, A., Trotman, L. C., Cheng, K., Varmeh, S., Kozma, S. C., Thomas, G., Rosivatz, E., Woscholski, R., Cognetti, F., Scher, H. I., Pandolfi, P. P. (2010) A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. Journal of Clinical Investigation, 120 (3). pp. 681-693. ISSN 00219738 (ISSN)

B

Baker, S., Cantley, L., Paolo Pandolfi, P., Parsons, R. (2010) PTEN PATHWAYS & TARGETS. In: 2010 meeting of PTEN PATHWAYS & TARGETS, March 16–March 20, 2010, Cold Spring Harbor Laboratory.

C

Chen, M., Nowak, D. G., Narula, N., Robinson, B., Watrud, K., Ambrico, A., Herzka, T. M., Zeeman, M. E., Minderer, M., Zheng, W., Ebbesen, S. H., Plafker, K. S., Stahlhut, C., Wang, V. M., Wills, L., Nasar, A., Castillo-Martin, M., Cordon-Cardo, C., Wilkinson, J. E., Powers, S., Sordella, R., Altorki, N. K., Mittal, V., Stiles, B. M., Plafker, S. M., Trotman, L. C. (2017) The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol, 216 (3). pp. 641-656. ISSN 0021-9525

Chen, M. H., Herzka, T. M., Zeeman, M. E., Plafker, K. S., Minderer, M., Castillo-Martin, M., Cordon-Cardo, C., Plafker, S. M., Trotman, L. C. (2013) PTEN levels are controlled by a nuclear transport receptor in lung cancer. Cancer Research, 73 (8 (Sup). p. 5258. ISSN 0008-5472

Chen, M. H., Pratt, C. P., Zeeman, M. E., Schultz, N., Taylor, B. S., O'Neill, A., Castillo-Martin, M., Nowak, D. G., Naguib, A., Grace, D. M., Murn, J., Navin, N., Atwal, G. S., Sander, C., Gerald, W. L., Cordon-Cardo, C., Newton, A. C., Carver, B. S., Trotman, L. C. (2011) Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression. Cancer Cell, 20 (2). pp. 173-186. ISSN 1535-6108

Chen, Z., Trotman, L. C., Shaffer, D., Lin, H. K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., Cordon-Cardo, C., Pandolfi, P. P. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436 (7051). pp. 725-30. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Chen, Z., Trotman, L. C., Shaffer, D., Lin, H. K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., Cordon-Cardo, C., Pandolfi, P. P. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436 (7051). pp. 725-30. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Cho, H., Herzka, T., Zheng, W., Qi, J., Wilkinson, J. E., Bradner, J. E., Robinson, B. D., Castillo-Martin, M., Cordon-Cardo, C., Trotman, L. C. (2014) RapidCaP, a novel GEM model for analysis and therapy of metastatic prostate cancer, reveals Myc as a driver of Pten-mutant metastasis. Cancer Discovery, 4 (3). pp. 318-33. ISSN 21598274

Cho, Hyejin, Herzka, Tali, Stahlhut, Carlos, Watrud, Kaitlin, Robinson, Brian D., Trotman, Lloyd C. (2015) Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome. Methods, 77-78. pp. 197-204. ISSN 1046-2023

F

Feng, Z. H., Hu, W. W., De Stanchina, E., Teresky, A. K., Jin, S. K., Lowe, S. W., Levine, A. J. (2007) The regulation of AMPK beta 1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Research, 67 (7). pp. 3043-3053. ISSN 0008-5472

H

Hernando, E., Charytonowicz, E., Dudas, M. E., Menendez, S., Matushansky, I., Mills, J., Socci, N. D., Behrendt, N., Ma, L., Maki, R. G., Pandolfi, P. P., Cordon-Cardo, C. (2007) The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nat Med, 13 (6). pp. 748-53. ISSN 1078-8956 (Print)1078-8956 (Linking)

Howitt, J., Lackovic, J., Low, L. H., Naguib, A., Macintyre, A., Goh, C. P., Callaway, J. K., Hammond, V., Thomas, T., Dixon, M., Putz, U., Silke, J., Bartlett, P., Yang, B. L., Kumar, S., Trotman, L. C., Tan, S. S. (2012) Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. Journal of Cell Biology, 196 (1). pp. 29-36. ISSN 0021-9525

I

Italiano, A., Chen, C. L., Thomas, R., Breen, M., Bonnet, F., Sevenet, N., Longy, M., Maki, R. G., Coindre, J. M., Antonescu, C. R. (2012) Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics. Cancer, 118 (23). pp. 5878-87. ISSN 1097-0142 (Electronic)0008-543X (Linking)

J

Janas, M. L., Hodson, D., Stamataki, Z., Hill, S., Welch, K., Gambardella, L., Trotman, L. C., Pandolfi, P. P., Vigorito, E., Turner, M. (2008) The Effect of Deleting p110{delta} on the Phenotype and Function of PTEN-Deficient B Cells. Journal of Immunology, 180 (2). pp. 739-46. ISSN 0022-1767

L

Labbe, D. P., Uetani, N., Vinette, V., Lessard, L., Aubry, I., Migon, E., Sirois, J., Haigh, J., Begin, L. R., Trotman, L. C., Paquet, M., Tremblay, M. L. (2016) PTP1B deficiency enables the ability of a high fat diet to drive the invasive character of PTEN-deficient prostate cancers. Cancer Res, 76 (11). pp. 3130-3135. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472

Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., Parsons, R. (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275 (5308). pp. 1943-7. ISSN 0036-8075 (Print)

M

Mathew, G., Hannan, A., Hertzler-Schaefer, K., Wang, F., Feng, G. S., Zhong, J., Zhao, J. J., Downward, J., Zhang, X. (2016) Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor. Proc Natl Acad Sci U S A, 113 (46). pp. 13156-13161. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Mayo, L. D., Dixon, J. E., Durden, D. L., Tonks, N. K., Donner, D. B. (2002) PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. Journal of Biological Chemistry, 277 (7). pp. 5484-5489. ISSN 0021-9258

Miething, C., Scuoppo, C., Bosbach, B., Appelmann, I., Nakitandwe, J., Ma, J., Wu, G., Lintault, L., Auer, M., Premsrirut, P. K., Teruya-Feldstein, J., Hicks, J., Benveniste, H., Speicher, M. R., Downing, J. R., Lowe, S. W. (2014) PTEN action in leukaemia dictated by the tissue microenvironment. Nature, 510 (7505). p. 402. ISSN 0028-0836

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., Tonks, N. K. (1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 94 (17). pp. 9052-7. ISSN 0027-8424 (Print)

Myers, M. P., Tonks, N. K. (1997) PTEN: Sometimes taking it off can be better than putting it on. American Journal of Human Genetics, 61 (6). pp. 1234-1238. ISSN 0002-9297

N

Naguib, A., Bencze, G., Engle, D. D., Chio, II, Herzka, T., Watrud, K., Bencze, S., Tuveson, D. A., Pappin, D. J., Trotman, L. C. (2014) P53 Mutations Change Phosphatidylinositol Acyl Chain Composition. Cell Reports, 10 (1). pp. 8-19. ISSN 2211-1247

Naguib, A., Bencze, G., Faehnle, C. R., Schalch, T., Lazar, Z., Ruse, C. I., Joshua-Tor, L., Pappin, D. J., Trotman, L. C. (2013) Upstream activation of PTEN. Cancer Research, 73 (8 (Sup). p. 5156. ISSN 0008-5472

Naguib, A., Trotman, L. C. (2013) PTEN plasticity: how the taming of a lethal gene can go too far. Trends In Cell Biology, 23 (8). pp. 374-379. ISSN 0962-8924

Naguib, Adam, Bencze, Gyula, Cho, Hyejin, Zheng, Wu, Tocilj, Ante, Elkayam, Elad, Faehnle, Christopher R, Jaber, Nadia, Pratt, Christopher P, Chen, Muhan, Zong, Wei-Xing, Marks, Michael S, Joshua-Tor, Leemor, Pappin, Darryl J, Trotman, Lloyd C (2015) PTEN Functions by Recruitment to Cytoplasmic Vesicles. Molecular Cell, 58 (2). pp. 255-268. ISSN 1097-2765

Nowak, D. G., Cho, H., Herzka, T., Wang, V. M. Y., Senturk, S., DeMarco, D. V., Ding, D., Fellmann, C., Beinortas, T., Kleinman, D., Watrud, K., Chen, M., Wilkinson, J. E., Castillo-Martin, M., Cordon-Cardo, C., Robinson, B. D., Trotman, L. C. (2015) Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2. Cancer Research, 75 (Supple). Abstract 2258. ISSN 0008-5472

P

Pulido, R., Baker, S. J., Barata, J. T., Carracedo, A., Cid, V. J., Chin-Sang, I. D., Dave, V., den Hertog, J., Devreotes, P., Eickholt, B. J., Eng, C., Furnari, F. B., Georgescu, M. M., Gericke, A., Hopkins, B., Jiang, X., Lee, S. R., Losche, M., Malaney, P., Matias-Guiu, X., Molina, M., Pandolfi, P. P., Parsons, R., Pinton, P., Rivas, C., Rocha, R. M., Rodriguez, M. S., Ross, A. H., Serrano, M., Stambolic, V., Stiles, B., Suzuki, A., Tan, S. S., Tonks, N. K., Trotman, L. C., Wolff, N., Woscholski, R., Wu, H., Leslie, N. R. (2014) A Unified Nomenclature and Amino Acid Numbering for Human PTEN. Science signaling, 7 (332). pe15. ISSN 1937-9145

S

Schwertassek, U., Haque, A., Krishnan, N., Greiner, R., Weingarten, L., Dick, T. P., Tonks, N. K. (2014) Reactivation of oxidized PTP1B and PTEN by Thioredoxin 1. Febs Journal, 281 (16). pp. 3545-3558. ISSN 1742-464X

Stolarov, J., Chang, K., Reiner, A., Rodgers, L., Hannon, G. J., Wigler, M. H., Mittal, V. (2001) Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America, 98 (23). pp. 13043-13048. ISSN 0027-8424

T

Tonks, N. K., Myers, M. P. (1999) Structural assets of a tumor suppressor. Science, 286 (5447). pp. 2096-2097. ISSN 0036-8075

Torres, J., Rodriguez, J., Myers, M. P., Valiente, M., Graves, J. D., Tonks, N. K., Pulido, R. (2003) Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3 - Implications for the control of protein stability and PTEN-protein interactions. Journal of Biological Chemistry, 278 (33). pp. 30652-30660. ISSN 0021-9258

Trotman, L. C., Niki, M., Dotan, Z. A., Koutcher, J. A., Di Cristofano, A., Xiao, A., Khoo, A. S., Roy-Burman, P., Greenberg, N. M., Van Dyke, T., Cordon-Cardo, C., Pandolfi, P. P. (2003) Pten dose dictates cancer progression in the prostate. PLoS Biology, 1 (3). ISSN 1545-7885 (Electronic)1544-9173 (Linking)

Trotman, L. C., Nowak, D. G., Cho, H., Herzka, T., Watrud, K., DeMarco, D. V., Wang, V. M., Senturk, S., Fellmann, C., Ding, D., Beinortas, T., Kleinman, D., Chen, M., Sordella, R., Wilkinson, J. E., Castillo-Martin, M., Cordon-Cardo, C., Robinson, B. D. (2015) Myc drives Pten/trp53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2. Cancer Discovery, 5 (6). pp. 636-651. ISSN 21598274

Trotman, L. C., Pandolfi, P. P. (2003) PTEN and p53: who will get the upper hand? Cancer Cell, 3 (2). pp. 97-9. ISSN 1535-6108 (Print)1535-6108 (Linking)

Trotman, L. C., Wang, X., Alimonti, A., Chen, Z., Teruya-Feldstein, J., Yang, H., Pavletich, N. P., Carver, B. S., Cordon-Cardo, C., Erdjument-Bromage, H., Tempst, P., Chi, S. G., Kim, H. J., Misteli, T., Jiang, X., Pandolfi, P. P. (2007) Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell, 128 (1). pp. 141-56.

W

Wang, X., Trotman, L. C., Koppie, T., Alimonti, A., Chen, Z., Gao, Z., Wang, J., Erdjument-Bromage, H., Tempst, P., Cordon-Cardo, C., Pandolfi, P. P., Jiang, X. (2007) NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN. Cell, 128 (1). pp. 129-139. ISSN 00928674 (ISSN)

Wen, S. H., Stolarov, J., Myers, M. P., Su, J. D., Wigler, M. H., Tonks, N. K., Durden, D. L. (2001) PTEN controls tumor-induced angiogenesis. Proceedings of the National Academy of Sciences of the United States of America, 98 (8). pp. 4622-4627. ISSN 0027-8424

Wendel, H. G., Malina, A., Zhao, Z., Zender, L., Kogan, S. C., Cordon-Cardo, C., Pelletier, J., Lowe, S. W. (2006) Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer Res, 66 (15). pp. 7639-46. ISSN 0008-5472 (Print)

X

Xiong, Q., Oviedo, H. V., Trotman, L. C., Zador, A. M. (2012) PTEN Regulation of Local and Long-Range Connections in Mouse Auditory Cortex. Journal of Neuroscience, 32 (5). pp. 1643-52. ISSN 0270-6474

Y

Ying, H. Q., Elpek, K. G., Vinjamoori, A., Zimmerman, S. M., Chu, G. C., Yan, H. Y., Fletcher-Sananikone, E., Zhang, H. L., Liu, Y. C., Wang, W., Ren, X. J., Zheng, H. W., Kimmelman, A. C., Paik, J. H., Lim, C., Perry, S. R., Jiang, S., Malinn, B., Protopopov, A., Colla, S., Xiao, Y. H., Hezel, A. F., Bardeesy, N., Turley, S. J., Wang, Y. A. A., Chin, L., Thayer, S. P., DePinho, R. A. (2011) PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-kappa B-Cytokine Network. Cancer Discovery, 1 (2). pp. 158-169. ISSN 2159-8274

Z

Zhang, X. C., Piccini, A., Myers, M. P., Van Aelst, L., Tonks, N. K. (2012) Functional analysis of the protein phosphatase activity of PTEN. Biochem J, 444 (3). pp. 457-64. ISSN 1470-8728 (Electronic)0264-6021 (Linking)

Zheng, H., Ying, H., Yan, H., Kimmelman, A. C., Hiller, D. J., Chen, A. J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z., Stommel, J. M., Dunn, K. L., Wiedemeyer, R., You, M. J., Brennan, C., Wang, Y. A., Ligon, K. L., Wong, W. H., Chin, L., dePinho, R. A. (2008) Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harbor Symposia on Quantitative Biology, 73. pp. 427-37. ISSN 0091-7451

Zheng, H. W., Ying, H. Q., Yan, H. Y., Kimmelman, A. C., Hiller, D. J., Chen, A. J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z. H., Stommel, J. M., Dunn, K. L., Wiedemeyer, R., You, M. J. J., Brennan, C., Wang, Y. A., Ligon, K. L., Wong, W. H., Chin, L., DePinho, R. A. (2008) p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature, 455 (7216). 1129-U13. ISSN 0028-0836

This list was generated on Mon May 29 16:54:00 2017 EDT.
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving