Browse by CSHL Author

Paper

Li, F., Deng, Z., Zhang, L., Wu, C., Jin, Y., Hwang, I., Vladimirova, O., Xu, L., Yang, L., Lu, B., Dheekollu, J., Li, J. Y., Feng, H., Hu, J., Vakoc, C. R., Ying, H., Paik, J., Lieberman, P. M., Zheng, H. (August 2019) ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization. Embo j, 38 (19). e96659. ISSN 0261-4189

Hwang, I., Cao, D., Na, Y., Kim, D. Y., Zhang, T., Yao, J., Oh, H., Hu, J., Zheng, H., Yao, Y., Paik, J. (March 2018) Far Upstream Element-Binding Protein 1 Regulates LSD1 Alternative Splicing to Promote Terminal Differentiation of Neural Progenitors. Stem Cell Reports, 10 (4). pp. 1208-1221. ISSN 2213-6711 (Electronic)2213-6711 (Linking)

Calvert, A. E., Chalastanis, A., Wu, Y., Hurley, L. A., Kouri, F. M., Bi, Y., Kachman, M., May, J. L., Bartom, E., Hua, Y., Mishra, R. K., Schiltz, G. E., Dubrovskyi, O., Mazar, A. P., Peter, M. E., Zheng, H., James, C. D., Burant, C. F., Chandel, N. S., Davuluri, R. V., Horbinski, C., Stegh, A. H. (May 2017) Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. Cell Rep, 19 (9). pp. 1858-1873.

Singh, Dinesh K., Kollipara, Rahul K., Vemireddy, Vamsidara, Yang, Xiao-Li, Sun, Yuxiao, Regmi, Nanda, Klingler, Stefan, Hatanpaa, Kimmo J., Raisanen, Jack, Cho, Steve K., Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara, Mashimo, Tomoyuki, Wang, Shan, Humphries, Caroline G., Mickey, Bruce, Maher, Elizabeth A., Zheng, Hongwu, Kim, Ryung S., Kittler, Ralf, Bachoo, Robert M. (January 2017) Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Reports, 18 (4). pp. 961-976. ISSN 2211-1247

Klingler, S., Guo, B., Yao, J., Yan, H., Zhang, L., Vaseva, A. V., Chen, S., Canoll, P., Horner, J. W., Wang, Y. A., Paik, J. H., Ying, H., Zheng, H. (May 2015) Development of resistance to EGFR targeted therapy in malignant glioma can occur through EGFR dependent and independent mechanisms. Cancer Research, 75 (10). pp. 2109-2119. ISSN 0008-5472

Hu, J., Ho, A. L., Yuan, L., Hu, B., Hua, S., Hwang, S. S., Zhang, J., Hu, T., Zheng, H., Gan, B., Wu, G., Wang, Y. A., Chin, L., DePinho, R. A. (August 2013) Neutralization of terminal differentiation in gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America, 110 (36). pp. 14520-14527. ISSN 00278424 (ISSN)

Zhang, Y., Shin, S. J., Liu, D., Ivanova, E., Foerster, F., Ying, H., Zheng, H., Xiao, Y., Chen, Z., Protopopov, A., Depinho, R. A., Paik, J. H. (June 2013) ZNF365 Promotes Stability of Fragile Sites and Telomeres. Cancer Discovery, 3 (7). pp. 798-811. ISSN 21598274

Ying, H. Q., Kimmelman, A. C., Lyssiotis, C. A., Hua, S. J., Chu, G. C., Fletcher-Sananikone, E., Locasale, J. W., Son, J., Zhang, H. L., Coloff, J. L., Yan, H. Y., Wang, W., Chen, S. J., Viale, A., Zheng, H. W., Paik, J. H., Lim, C., Guimaraes, A. R., Martin, E. S., Chang, J., Hezel, A. F., Perry, S. R., Hu, J., Gan, B. Y., Xiao, Y. H., Asara, J. M., Weissleder, R., Wang, Y. A., Chin, L., Cantley, L. C., DePinho, R. A. (April 2012) Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell, 149 (3). pp. 656-670. ISSN 0092-8674

Genovese, G., Ergun, A., Shukla, S. A., Campos, B., Hanna, J., Ghosh, P., Quayle, S. N., Rai, K., Colla, S., Ying, H., Wu, C. J., Sarkar, S., Xiao, Y., Zhang, J., Zhang, H., Kwong, L., Dunn, K., Wiedemeyer, W. R., Brennan, C., Zheng, H., Rimm, D. L., Collins, J. J., Chin, L. (2012) microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. Cancer Discovery, 2 (8). pp. 736-749.

Ying, H. Q., Elpek, K. G., Vinjamoori, A., Zimmerman, S. M., Chu, G. C., Yan, H. Y., Fletcher-Sananikone, E., Zhang, H. L., Liu, Y. C., Wang, W., Ren, X. J., Zheng, H. W., Kimmelman, A. C., Paik, J. H., Lim, C., Perry, S. R., Jiang, S., Malinn, B., Protopopov, A., Colla, S., Xiao, Y. H., Hezel, A. F., Bardeesy, N., Turley, S. J., Wang, Y. A. A., Chin, L., Thayer, S. P., DePinho, R. A. (July 2011) PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-kappa B-Cytokine Network. Cancer Discovery, 1 (2). pp. 158-169. ISSN 2159-8274

Ding, Z. H., Wu, C. J., Chu, G. C., Xiao, Y. H., Ho, D., Zhang, J. F., Perry, S. R., Labrot, E. S., Wu, X. Q., Lis, R., Hoshida, Y., Hiller, D., Hu, B. L., Jiang, S., Zheng, H. W., Stegh, A. H., Scott, K. L., Signoretti, S., Bardeesy, N., Wang, Y. A., Hill, D. E., Golub, T. R., Stampfer, M. J., Wong, W. H., Loda, M., Mucci, L., Chin, L., DePinho, R. A. (February 2011) SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature, 470 (7333). pp. 269-73. ISSN 0028-0836

Gan, B. Y., Lim, C., Chu, G., Hua, S. J., Ding, Z. H., Collins, M., Hu, J. A., Jiang, S., Fletcher-Sananikone, E., Zhuang, L., Chang, M., Zheng, H. W., Wang, Y. A., Kwiatkowski, D. J., Kaelin, W. G., Signoretti, S., DePinho, R. A. (November 2010) FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis. Cancer Cell, 18 (5). pp. 472-484. ISSN 1535-6108

Zheng, H. W., Ying, H. Q., Wiedemeyer, R., Yan, H. Y., Quayle, S. N., Ivanova, E. V., Paik, J. H., Zhang, H. L., Xiao, Y. H., Perry, S. R., Hu, J., Vinjamoori, A., Gan, B. Y., Sahin, E., Chheda, M. G., Brennan, C., Wang, Y. A., Hahn, W. C., Chin, L., DePinho, R. A. (May 2010) PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas. Cancer Cell, 17 (5). pp. 497-509. ISSN 1535-6108

Ying, H. Q., Zheng, H. W., Scott, K., Wiedemeyer, R., Yan, H. Y., Lim, C., Huang, J., Dhakal, S., Ivanova, E., Xiao, Y. H., Zhang, H. L., Hu, J., Stommel, J. M., Lee, M. A., Chen, A. J., Paik, J. H., Segatto, O., Brennan, C., Elferink, L. A., Wang, Y. A., Chin, L., DePinho, R. A. (April 2010) Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America, 107 (15). pp. 6912-6917. ISSN 0027-8424

Paik, J. H., Ding, Z. H., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S. S., Zheng, H. W., Ying, H. Q., Mahoney, J., Hiller, D., Jiang, S., Protopopov, A., Wong, W. H., Chin, L., Ligon, K. L., DePinho, R. A. (November 2009) FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis. Cell Stem Cell, 5 (5). pp. 540-553. ISSN 1934-5909

Kimmelman, A. C., Hezel, A. F., Aguirre, A. J., Zheng, H. W., Paik, J. H., Ying, H. Q., Chu, G. C., Zhang, J. X., Sahin, E., Yeo, G. M., Ponugoti, A., Nabioullin, R., Deroo, S., Yang, S. D., Wang, X. X., McGrath, J. P., Protopopova, M., Ivanova, E., Zhang, J. H., Feng, B., Tsao, M. S., Redston, M., Protopopov, A., Xiao, Y. H., Futreal, P. A., Hahn, W. C., Klimstra, D. S., Chin, L., DePinho, R. A. (December 2008) Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America, 105 (49). pp. 19372-19377. ISSN 0027-8424

Zheng, H. W., Ying, H. Q., Yan, H. Y., Kimmelman, A. C., Hiller, D. J., Chen, A. J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z. H., Stommel, J. M., Dunn, K. L., Wiedemeyer, R., You, M. J. J., Brennan, C., Wang, Y. A., Ligon, K. L., Wong, W. H., Chin, L., DePinho, R. A. (October 2008) p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature, 455 (7216). 1129-U13. ISSN 0028-0836

Zheng, H., Ying, H., Yan, H., Kimmelman, A. C., Hiller, D. J., Chen, A. J., Perry, S. R., Tonon, G., Chu, G. C., Ding, Z., Stommel, J. M., Dunn, K. L., Wiedemeyer, R., You, M. J., Brennan, C., Wang, Y. A., Ligon, K. L., Wong, W. H., Chin, L., dePinho, R. A. (2008) Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma. Cold Spring Harbor Symposia on Quantitative Biology, 73. pp. 427-37. ISSN 0091-7451

Sdek, P., Ying, H. Q., Chang, D. L. F., Qiu, W., Zheng, H. W., Touitou, R., Allday, M. J., Xiao, Z. X. J. (December 2005) MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. Molecular Cell, 20 (5). pp. 699-708. ISSN 1097-2765

Ying, H. Q., Chang, D. L. F., Zheng, H. W., McKeon, F., Xiao, Z. X. J. (July 2005) DNA-binding and transactivation activities are essential for TAp63 protein degradation. Molecular and Cellular Biology, 25 (14). pp. 6154-6164. ISSN 0270-7306

Sdek, P., Ying, H. Q., Zheng, H. W., Margulis, A., Tang, X. R., Tian, K., Xiao, Z. X. J. (December 2004) The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth. Journal of Biological Chemistry, 279 (51). pp. 53317-53322. ISSN 0021-9258

Gu, L., Ying, H. Q., Zheng, H. W., Murray, S. A., Xiao, Z. X. J. (June 2003) The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression. Febs Letters, 544 (1-3). pp. 218-222. ISSN 0014-5793

Gu, L., Zheng, H. W., Murray, S. A., Ying, H. Q., Xiao, Z. X. J. (March 2003) Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis. Biochemical and Biophysical Research Communications, 302 (2). pp. 384-391. ISSN 0006-291X

Murray, S. A., Zheng, H. W., Gu, L., Xiao, Z. X. J. (March 2003) IGF-1 activates p21 to inhibit UV-induced cell death. Oncogene, 22 (11). pp. 1703-1711. ISSN 0950-9232

Zheng, H. W., You, H., Zhou, X. Z., Murray, S. A., Uchida, T., Wulf, G., Gu, L., Tang, X. R., Lu, K. P., Xiao, Z. X. J. (October 2002) The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature, 419 (6909). pp. 849-853. ISSN 0028-0836

You, H., Zheng, H. W., Murray, S. A., Yu, Q., Uchida, T., Fan, D. M., Xiao, Z. X. J. (2002) IGF-1 induces Pin1 expression in promoting cell cycle S-phase entry. Journal of Cellular Biochemistry, 84 (2). pp. 211-216. ISSN 0730-2312

Wang, Y. L., Zheng, H. W., Liu, X. L., Zhang, Y. Z. (July 1998) High efficient expression in Escherichia coli of chitinase gene cloned from Bacillus circulans C-2. Acta Biochimica Et Biophysica Sinica, 30 (4). pp. 352-356. ISSN 0582-9879

Zeng, H., Wang, Y., Zhang, Y. (1998) Molecular cloning of a chitinase gene from Bacillus circulans C-2. Chinese Journal of Biotechnology, 14 (1). pp. 25-9. ISSN 1042-749X

Video

Zheng, H. (November 2011) Talk from Hongwu Zheng at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)