Browse by CSHL Author

Ubhi, Tajinder, Zaslaver, Olga, Quaile, Andrew T, Plenker, Dennis, Cao, Pinjiang, Pham, Nhu-An, Békési, Angéla, Jang, Gun-Ho, O'Kane, Grainne M, Notta, Faiyaz, Moffat, Jason, Wilson, Julie M, Gallinger, Steven, Vértessy, Beáta G, Tuveson, David A, Röst, Hannes L, Brown, Grant W (March 2024) Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature Cancer. ISSN 2662-1347 (Public Dataset)

Demyan, Lyudmyla, Habowski, Amber N, Plenker, Dennis, King, Daniel A, Standring, Oliver J, Tsang, Caitlin, St Surin, Luce, Rishi, Arvind, Crawford, James M, Boyd, Jeff, Pasha, Shamsher A, Patel, Hardik, Galluzzo, Zachary, Metz, Christine, Gregersen, Peter K, Fox, Sharon, Valente, Cristina, Abadali, Sonya, Matadial-Ragoo, Steffi, DePeralta, Danielle K, Deutsch, Gary B, Herman, Joseph M, Talamini, Mark A, Tuveson, David A, Weiss, Matthew J (September 2022) Pancreatic Cancer Patient-derived Organoids Can Predict Response to Neoadjuvant Chemotherapy. Annals of Surgery, 276 (3). pp. 450-462. ISSN 0003-4932

Fernandez-Vega, Virneliz, Hou, Shurong, Plenker, Dennis, Tiriac, Hervé, Baillargeon, Pierre, Shumate, Justin, Scampavia, Louis, Seldin, Jan, Souza, Glauco R, Tuveson, David A, Spicer, Timothy P (March 2022) Lead Identification using 3D Models of Pancreatic Cancer: Development of 3D Tumor Models for High-throughput Screening. Slas Discovery. ISSN 2472-5552

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Knox, Jennifer J, Jaffee, Elizabeth M, O'Kane, Grainne M, Plenker, Dennis, Zhang, Amy, Ramotar, Stephanie, Dodd, Anna, Prince, Rebecca M, Laheru, Dan, Yu, Kenneth H, Saif, Wasif M, Elimova, Elena, Pishvaian, Michael J, Perez, Kimberly, Aguirre, Andrew, Fischer, Sandra, Wilson, Julie, Notta, Faiyaz, Tuveson, David A, Gallinger, Steven (February 2022) PASS-01: Pancreatic adenocarcinoma signature stratification for treatment-01. In: 2022 ASCO Gastrointestinal Cancers Symposium.

Soroka, Stanley, Plenker, Dennis, Patel, Hardik, Habowski, Amber, Tuveson, David, Martello-Rooney, Laura (2022) Characterization of gemcitabine- and paclitaxel-loaded poly(lactic-co-glycolic acid) microparticles as a treatment for pancreatic ductal adenocarcinoma using in vitro models. In: Annual Meeting of the American-Association-for-Cancer-Research (AACR), APR 08-13, 2022, New Orleans, LA.

Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F, Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A, Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K, Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S, Li, Henry, Schmitt, Clemens A, George, Julie, Thomas, Roman K, von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T, Siveke, Jens T, Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L (September 2021) MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature Communications, 12 (1). p. 5505. ISSN 2041-1723

Moore, Keith J. M., Cahill, Jeremy, Aidelberg, Guy, Aronoff, Rachel, Bektaş, Ali, Bezdan, Daniela, Butler, Daniel J., Chittur, Sridar V., Codyre, Martin, Federici, Fernan, Tanner, Nathan A., Tighe, Scott W., True, Randy, Ware, Sarah B., Wyllie, Anne L., Afshin, Evan E., Bendesky, Andres, Chang, Connie B., Dela Rosa, Richard, Elhaik, Eran, Erickson, David, Goldsborough, Andrew S., Grills, George, Hadasch, Kathrin, Hayden, Andrew, Her, Seong-Young, Karl, Julie A., Kim, Chang Hee, Kriegel, Alison J., Kunstman, Thomas, Landau, Zeph, Land, Kevin, Langhorst, Bradley W., Lindner, Ariel B., Mayer, Benjamin E., McLaughlin, Lee A., McLaughlin, Matthew T., Molloy, Jenny, Mozsary, Christopher, Nadler, Jerry L., D'Silva, Melinee, Ng, David, O'Connor, David H., Ongerth, Jerry E., Osuolale, Olayinka, Pinharanda, Ana, Plenker, Dennis, Ranjan, Ravi, Rosbash, Michael, Rotem, Assaf, Segarra, Jacob, Schürer, Stephan, Sherrill-Mix, Scott, Solo-Gabriele, Helena, To, Shaina, Vogt, Merly C., Yu, Albert D., Mason, Christopher E. (September 2021) Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications. Journal of Biomolecular Techniques : JBT, 32 (3). pp. 228-275. ISSN 1524-0215

Lyons, Scott K, Plenker, Dennis, Trotman, Lloyd C (July 2021) Advances in preclinical evaluation of experimental antibody-drug conjugates. Cancer Drug Resistance, 4. pp. 745-754. ISSN 2578-532X

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall E, Tuveson, David A, Tsai, Susan, Haab, Brian B (January 2021) Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA. Clinical Cancer Research, 27 (1). pp. 226-236. ISSN 1078-0432

Dreyer, Stephan B, Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc, Moran-Jones, Kim, Wright, Derek W, Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J, McGregor, Grant A, Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L, Candido, Juliana, Balkwill, Frances, Barry, Simon T, Grützmann, Robert, Rahib, Lola, Glasgow Precision Oncology Laboratory,, Australian Pancreatic Cancer Genome Initiative, Johns, Amber, Pajic, Marina, Froeling, Fieke EM, Beer, Phillip, Musgrove, Elizabeth A, Petersen, Gloria M, Ashworth, Alan, Frame, Margaret C, Crawford, Howard C, Simeone, Diane M, Lord, Chris, Mukhopadhyay, Debabrata, Pilarsky, Christian, Tuveson, David A, Cooke, Susanna L, Jamieson, Nigel B, Morton, Jennifer P, Sansom, Owen J, Bailey, Peter J, Biankin, Andrew V, Chang, David K (January 2021) Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer. Gastroenterology, 160 (1). 362-377.e13. ISSN 0016-5085

Froeling, Fieke E.M., Plenker, Dennis, O’Kane, Grainne, Aguirre, Andrew J., Wolpin, Brian M., Laheru, Daniel A., Saif, M Wasif, Yu, Kenneth H., Fischer, Sandra, Gallinger, Steven, Knox, Jennifer J., Jaffee, Elizabeth M., Tuveson, David A. (September 2020) Organoid Personalized Therapeutics and the Pancreatic Adenocarcinoma Signature Stratification for treatment (PASS) – 01 trial. In: The London Pancreas Workshop 2020.

Oni, Tobiloba E, Bautista, Carmelita, Merrill, Joseph R, Goos, Jeroen ACM, Rivera, Keith D, Miyabayashi, Koji, Biffi, Giulia, Garcia, Libia, Plenker, Dennis, Patel, Hardik, Elyada, Ela, Samaritano, Maria, Yu, Kenneth H, Pappin, Darryl J, Goggins, Michael G, Hruban, Ralph H, Lewis, Jason S, Lyons, Scott K, Yeh, Johannes T, Tuveson, David A (September 2020) Detection of incipient pancreatic cancer with novel tumor-specific antibodies in mouse models. BioRxiv. (Unpublished)

Seppälä, Toni T, Zimmerman, Jacquelyn W, Sereni, Elisabetta, Plenker, Dennis, Suri, Reecha, Rozich, Noah, Blair, Alex, Thomas, Dwayne L, Teinor, Jonathan, Javed, Ammar, Patel, Hardik, Cameron, John L, Burns, William R, He, Jin, Tuveson, David A, Jaffee, Elizabeth M, Eshleman, James, Szabolcs, Annamaria, Ryan, David P, Ting, David T, Wolfgang, Christopher L, Burkhart, Richard A (September 2020) Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. Annals of Surgery, 272 (3). pp. 427-435. ISSN 0003-4932

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall, Tuveson, David, Tsai, Susan, Haab, Brian (September 2020) Detection of chemotherapy-resistant pancreatic cancer using a glycan Biomarker. In: AACR Virtual Special Conference on Pancreatic Cancer.

LaComb, J. F., Plenker, D., Tiriac, H., Bucobo, J. C., D'Souza, L.S., Khokhar, A.S., Patel, H., Channer, B., Joseph, D., Wu, M., Tuveson, D. A., Li, E., Buscaglia, J. M. (February 2020) Single-Pass vs 2-Pass Endoscopic Ultrasound-Guided Fine-Needle Biopsy Sample Collection for Creation of Pancreatic Adenocarcinoma Organoids. Clin Gastroenterol Hepatol. ISSN 1542-3565

Sugarman, R., Patel, R., Sharma, S., Plenker, D., Tuveson, D., Saif, M. W. (July 2019) Pharmacokinetics and pharmacodynamics of new drugs for pancreatic cancer. Expert Opin Drug Metab Toxicol, 15 (7). pp. 541-552. ISSN 1742-5255

Tiriac, H., Plenker, D., Baker, L. A., Tuveson, D. A. (March 2019) Organoid models for translational pancreatic cancer research. Curr Opin Genet Dev, 54. pp. 7-11. ISSN 0959-437x

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschenes, A., Somerville, T., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., LaComb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. A., Johnson, M., Arora, K., Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E. D., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P. J., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O'Kane, G. M., Notta, F., Kim, E. J., Crawford, J. M., Devoe, C. E., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R. A., Knox, J. J., Krasnitz, A., Gallinger, S., Tuveson, D. A. (May 2018) Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery, 8 (9). pp. 1112-1129. ISSN 21598274 (Public Dataset)

Plenker, D., Bertrand, M., de Langen, A. J., Riedel, R., Lorenz, C., Scheel, A. H., Muller, J., Bragelmann, J., Dassler-Plenker, J., Kobe, C., Persigehl, T., Kluge, A., Wurdinger, T., Schellen, P., Hartmann, G., Zacherle, T., Menon, R., Thunnissen, E., Buttner, R., Griesinger, F., Wolf, J., Heukamp, L., Sos, M. L., Heuckmann, J. M. (March 2018) Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients. Clin Cancer Res, 24 (6). pp. 1337-1343. ISSN 1078-0432 (Print)1078-0432