Additional materials of the author at
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Greenberg, E., Tung, E. S., Gauvin, C., Osiecki, L., Yang, K. G., Curley, E., Essa, A., Illmann, C., Sandor, P., Dion, Y., Lyon, G. J., King, R. A., Darrow, S., Hirschtritt, M. E., Budman, C. L., Grados, M., Pauls, D. L., Keuthen, N. J., Mathews, C. A. , Scharf, J. M. (2018) Prevalence and predictors of hair pulling disorder and excoriation disorder in Tourette syndrome. Eur Child Adolesc Psychiatry, 27(5) pp. 569-579.

Fang, Han, Huang, Yi-Fei, Radhakrishnan, Aditya, Siepel, Adam, Lyon, Gholson J. , Schatz, Michael C. (2018) Scikit-ribo Enables Accurate Estimation and Robust Modeling of Translation Dynamics at Codon Resolution. Cell Systems, 6(2) pp. 180-191.

Darrow, Sabrina M., Grados, Marco, Sandor, Paul, Hirschtritt, Matthew E., Illmann, Cornelia, Osiecki, Lisa, Dion, Yves, King, Robert, Pauls, David, Budman, Cathy L., Cath, Danielle C., Greenberg, Erica, Lyon, Gholson J., McMahon, William M., Lee, Paul C., Delucchi, Kevin L., Scharf, Jeremiah M. , Mathews, Carol A. (2017) Autism Spectrum Symptoms in a Tourette Syndrome Sample. Journal of the American Academy of Child & Adolescent Psychiatry, 56(7) pp. 610-617.

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Hirschtritt, Matthew, Darrow, Sabrina M., Illmann, Cornelia, Osiecki, Lisa, Grados, Marco, Sandor, Paul, Dion, Yves, King, Robert A., Pauls, David, Budman, Cathy L., Cath, Danielle C., Greenberg, Erica, Lyon, Gholson J., Yu, Dongmei, McGrath, Lauren M., McMahon, William M., Lee, Paul C., Delucchi, Kevin L., Scharf, Jeremiah M. , Mathews, Carol A. (2017) Genetic and Phenotypic Overlap of Specific Obsessive-Compulsive Subtypes with Tourette Syndrome. Biological Psychiatry, 81(10, Su) pp. S361-S362.

Willsey, A. J., Fernandez, T. V., Yu, D., King, R. A., Dietrich, A., Xing, J., Sanders, S. J., Mandell, J. D., Huang, A. Y., Richer, P., Smith, L., Dong, S., Samocha, K. E., Neale, B. M., Coppola, G., Mathews, C. A., Tischfield, J. A., Scharf, J. M., State, M. W. , Heiman, G. A. (2017) De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron, 94(3) pp. 486-499.e9.

Darrow, S. M., Hirschtritt, M. E., Davis, L. K., Illmann, C., Osiecki, L., Grados, M., Sandor, P., Dion, Y., King, R., Pauls, D., Budman, C. L., Cath, D. C., Greenberg, E., Lyon, G. J., Yu, D., McGrath, L. M., McMahon, W. M., Lee, P. C., Delucchi, K. L., Scharf, J. M. , Mathews, C. A. (2017) Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome. Am J Psychiatry, 174(4) pp. 387-396.

Fang, H., Wu, Y., Yang, H., Yoon, M., Jimenez-Barron, L. T., Mittelman, D., Robison, R., Wang, K. , Lyon, G. J. (2017) Whole genome sequencing of one complex pedigree illustrates challenges with genomic medicine. BMC Med Genomics, 10(1) pp. 10.

Dorfel, M. J., Fang, H., Crain, J., Klingener, M., Weiser, J. , Lyon, G. J. (2017) Proteomic and genomic characterization of a yeast model for Ogden syndrome. Yeast, 34(1) pp. 19-37.

Fang, H., Bergmann, E. A., Arora, K., Vacic, V., Zody, M. C., Iossifov, I., O'Rawe, J. A., Wu, Y., Jimenez Barron, L. T., Rosenbaum, J., Ronemus, M., Lee, Y. H., Wang, Z., Dikoglu, E., Jobanputra, V., Lyon, G. J., Wigler, M., Schatz, M. C. , Narzisi, G. (2016) Indel variant analysis of short-read sequencing data with Scalpel. Nat Protoc, 11(12) pp. 2529-2548.

Kleyner, R., Malcolmson, J., Tegay, D., Ward, K., Maughan, A., Maughan, G., Nelson, L., Wang, K., Robison, R. , Lyon, G. J. (2016) KBG syndrome involving a single-nucleotide duplication in ANKRD11. Cold Spring Harb Mol Case Stud, 2(6) pp. a001131.

Malcolmson, J., Kleyner, R., Tegay, D., Adams, W., Ward, K., Coppinger, J., Nelson, L., Meisler, M. H., Wang, K., Robison, R. , Lyon, G. J. (2016) SCN8A mutation in a child presenting with seizures and developmental delays. Cold Spring Harb Mol Case Stud, 2(6) pp. a001073.

Hirschtritt, M. E., Darrow, S. M., Illmann, C., Osiecki, L., Grados, M., Sandor, P., Dion, Y., King, R. A., Pauls, D. L., Budman, C. L., Cath, D. C., Greenberg, E., Lyon, G. J., Yu, D., McGrath, L. M., McMahon, W. M., Lee, P. C., Delucchi, K. L., Scharf, J. M. , Mathews, C. A. (2016) Social disinhibition is a heritable subphenotype of tics in Tourette syndrome. Neurology, 87(5) pp. 497-504.

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Kohler, S., Vasilevsky, N. A., Engelstad, M., Foster, E., McMurry, J., Ayme, S., Baynam, G., Bello, S. M., Boerkoel, C. F., Boycott, K. M., Brudno, M., Buske, O. J., Chinnery, P. F., Cipriani, V., Connell, L. E., Dawkins, H. J., DeMare, L. E., Devereau, A. D., de Vries, B. B., Firth, H. V., Freson, K., Greene, D., Hamosh, A., Helbig, I., Hum, C., Jahn, J. A., James, R., Krause, R., Laulederkind, S. J., Lochmuller, H., Lyon, G. J., Ogishima, S., Olry, A., Ouwehand, W. H., Pontikos, N., Rath, A., Schaefer, F., Scott, R. H., Segal, M., Sergouniotis, P. I., Sever, R., Smith, C. L., Straub, V., Thompson, R., Turner, C., Turro, E., Veltman, M. W., Vulliamy, T., Yu, J., von Ziegenweidt, J., Zankl, A., Zuchner, S., Zemojtel, T., Jacobsen, J. O., Groza, T., Smedley, D., Mungall, C. J., Haendel, M. , Robinson, P. N. (2016) The Human Phenotype Ontology in 2017. Nucleic Acids Res, 45(D1) pp. D865-D876.

O’Rawe, Jason A, Wu, Yiyang, Dörfel, Max J, Rope, Alan F, Au, P. Y.  Billie, Parboosingh, Jillian S, Moon, Sungjin, Kousi, Maria, Kosma, Konstantina, Smith, Christopher S, Tzetis, Maria, Schuette, Jane L, Hufnagel, Robert B, Prada, Carlos E, Martinez, Francisco, Orellana, Carmen, Crain, Jonathan, Caro-Llopis, Alfonso, Oltra, Silvestre, Monfort, Sandra, Jiménez-Barrón, Laura T, Swensen, Jeffrey, Ellingwood, Sara, Smith, Rosemarie, Fang, Han, Ospina, Sandra, Stegmann, Sander, Den Hollander, Nicolette, Mittelman, David, Highnam, Gareth, Robison, Reid, Yang, Edward, Faivre, Laurence, Roubertie, Agathe, Rivière, Jean-Baptiste, Monaghan, Kristin G, Wang, Kai, Davis, Erica E, Katsanis, Nicholas, Kalscheuer, Vera M, Wang, Edith H, Metcalfe, Kay, Kleefstra, Tjitske, Innes, A.  Micheil, Kitsiou-Tzeli, Sophia, Rosello, Monica, Keegan, Catherine E , Lyon, Gholson J (2015) TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations. The American Journal of Human Genetics, 97(6) pp. 922-932.

Jiménez-Barrón, Laura T., O'Rawe, Jason A., Wu, Yiyang, Yoon, Margaret, Fang, Han, Iossifov, Ivan , Lyon, Gholson J. (2015) Genome-wide variant analysis of simplex autism families with an integrative clinical-bioinformatics pipeline. Molecular Case Studies, 1(1)

Guo, Y., Ding, X., Shen, Y., Lyon, G. J. , Wang, K. (2015) SeqMule: automated pipeline for analysis of human exome/genome sequencing data. Sci Rep, 5 pp. 14283.

Doerfel, Max , Lyon, Gholson J. (2015) The biological functions of Naa10 – from amino-terminal acetylation to human disease. Gene, 567(2) pp. 103-131.

Hirschtritt, M. E., Lee, P. C., Pauls, D. L., Dion, Y., Grados, M. A., Illmann, C., King, R. A., Sandor, P., McMahon, W. M., Lyon, G. J., Cath, D. C., Kurlan, R., Robertson, M. M., Osiecki, L., Scharf, J. M. , Mathews, C. A. (2015) Lifetime Prevalence, Age of Risk, and Genetic Relationships of Comorbid Psychiatric Disorders in Tourette Syndrome. JAMA Psychiatry, 72(4) pp. 325.

Lyon, Gholson J. (2015) Cut the Hype. Accuracy and Standards Come First.. Frontline Genomics, 2 pp. 19-23.

Hirschtritt, ME, Lee, PC, Pauls, DL, Dion, Yves, Grados, MA, Illmann, C, King, RA, Sandor, P., McMahon, W. M., Lyon, Gholson J., Cath, Danielle C., Kurlan, Roger, Robertson, M. M., Osiecki, L., Scharf, Jeremiah M. , Matthews, Carol A. (2015) Lifetime Prevalence, Age of Risk, and Etiology of Comorbid Psychiatric Disorders in Tourette Syndrome. Tourette Syndrome Association International Consortium for Genetics, JAMA Psychiatry.

He, M., Person, T. N., Hebbring, S. J., Heinzen, E., Ye, Z., Schrodi, S. J., McPherson, E. W., Lin, S. M., Peissig, P. L., Brilliant, M. H., O'Rawe, J., Robison, R. J., Lyon, G. J. , Wang, K. (2015) SeqHBase: a big data toolset for family based sequencing data analysis. Journal of Medical Genetics, 52(4) pp. 282-288.

O'Rawe, J. A., Ferson, S. , Lyon, G. J. (2015) Accounting for uncertainty in DNA sequencing data. Trends Genet, 31(2) pp. 61-68.

O'Rawe, Jason, Wu, Yiyang, Rope, Alan, Jimenez Barron, Laura, Swensen, Jeffrey J., Fang, Han, Mittelman, David, Highnam, Gareth, Robison, Reid J., Yang, Edward, Wang, Kai , Lyon, Gholson (2015) A variant in TAF1 is associated with a new syndrome with severe intellectual disability and characteristic dysmorphic features. bioRxiv,

Myklebust, L. M., Van Damme, P., Stove, S. I., Dorfel, M. J., Abboud, A., Kalvik, T. V., Grauffel, C., Jonckheere, V., Wu, Y., Swensen, J., Kaasa, H., Liszczak, G., Marmorstein, R., Reuter, N., Lyon, G. J., Gevaert, K. , Arnesen, T. (2014) Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Human Molecular Genetics, 24(7) pp. 1956-1976.

Barash, Carol Isaacson , Lyon, Gholson (2014) Open access and data sharing: Easier said than done. Applied & Translational Genomics, (0)

Narzisi, G., O'Rawe, Jason, Iossifov, I., Fang, Han, Lee, Y. H., Wang, Zihua, Wu, Yiyang, Lyon, Gholson J., Wigler, M. H. , Schatz, M. C. (2014) Accurate de novo and transmitted indel detection in exome-capture data using microassembly. Nature Methods, 11(10) pp. 1033-1036.

McGrath, Lauren M., Yu, Dongmei, Marshall, Christian, Davis, Lea K., Thiruvahindrapuram, Bhooma, Li, Bingbin, Cappi, Carolina, Geber, Gloria, Wolf, Aaron, Schroeder, Frederick A., Osiecki, Lisa, O'Dushlaine, Colm, Kirby, Andrew, Illman, Cornelia, Haddad, Stephen, Gallagher, Patience, Fagerness, Jesen A., Barr, Cathy L., Bellodi, Laura, Benarroch, Fortu, Bienvenu, O. Joseph, Black, Donald W., Bloch, Michael H., Bruun, Ruth D., Budman, Cathy L., Camarena, Beatriz, Cath, Danielle C., Cavallini, Maria C,, Chouinard, Sylvain, Coric, Vladimir, Cullen, Bernadette, Delomre, Richard, Denys, Damiaan, Derks, Eske M., Dion, Yves, Rosario, Maria C., Eapen, Valsama, Evans, Patrick, Falkai, Peter, Fernanadez, Thomas, Garrido, Helena, Geller, Daniel, Grabe, Hans J., Grados, Marco A., Greenberg, Benjamin D., Gross-Tsur, Varda, Grunblatt, Edna, Heiman, Gary A, Hemmings, Sian M.J., Herrera, Luis D., Hounie, Ana G., Jankovic, Joseph, Kennedy, James L., King, Robert A., Kurlan, Roger, Lanzagorta, Nuria, Leboyer, Marion, Leckman, James F., Lennertz, Leonhard, Lochner, Christine, Lowe, Thomas L., Lyon, Gholson J,, Maccaiardi, Fabio, Maier, Wolfgang, McCracken, James T., McMahon, William, Murphy, Dennis L., Naarden, Allan L., Neale, Benjamin M., Nurmi, Erika, Pakstis, Andrew J,, Pato, Michele T., Pato, Carlos N., Piacentini, John, Pittenger, Christopher, Pollak, Yehuda, Reus, Victor I., Richter, Maragret A., Riddle, Mark, Robertson, Mary M., Rosenberg, David, Rouleau, Guy A., Ruhrmann, Stephan, Sampaio, Aline S., Samuels, Jack, Sandor, Paul, Sheppard, Brooke, Singer, Harvey S., Smit, Jan H., Stein, Dan J., Tishfield, Jay A., Vallada, Homero, Veenstra-VanderWeele, Jeremy, Walitza, Susanne, Wang, Ying, Wendland, Jens R., Shugart, Yin Yao, Miguel, Euripedes C., Nicolini, Humberto, Oostra, Ben A., Moessner, Rainald, Wagner, Michael, Ruiz-Linares, Andres, Heutink, Peter, Nestadt, Gerald, Freimer, Nelson, Petryshen, Tracey, Posthuma, Danielle, Jenike, Michael A., Cox, Nancy J., Hanna, Gregory L., Brentani, Helena, Schrerer, Stephen W., Arnold, Paul D., Stewart, S. Evelyn, Matthews, Carol A., Knowles, James A., Cook, Edwin H., Pauls, David L., Wang, Kai , Scharf, Jeremiah M. (2014) Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study. Journal of American Academy of Child & Adolescent Psychiatry, 53(8) pp. 910-9.

Brownstein, C. A., Beggs, A. H., Homer, N., Merriman, B., Yu, T. W., Flannery, K. C., Dechene, E. T., Towne, M. C., Savage, S. K., Price, E. N., Holm, I. A., Luquette, L. J., Lyon, E., Majzoub, J., Neupert, P., McCallie, D., Szolovits, P., Willard, H. F., Mendelsohn, N. J., Temme, R., Finkel, R. S., Yum, S. W., Medne, L., Sunyaev, S. R., Adzhubey, I., Cassa, C. A., de Bakker, P. I., Duzkale, H., Dworzy Ski, P., Fairbrother, W., Francioli, L., Funke, B. H., Giovanni, M. A., Handsaker, R. E., Lage, K., Lebo, M. S., Lek, M., Leshchiner, I., Macarthur, D. G., McLaughlin, H. M., Murray, M. F., Pers, T. H., Polak, P. P., Raychaudhuri, S., Rehm, H. L., Soemedi, R., Stitziel, N. O., Vestecka, S., Supper, J., Gugenmus, C., Klocke, B., Hahn, A., Schubach, M., Menzel, M., Biskup, S., Freisinger, P., Deng, M., Braun, M., Perner, S., Smith, R. J., Andorf, J. L., Huang, J., Ryckman, K., Sheffield, V. C., Stone, E. M., Bair, T., Black-Ziegelbein, E. A., Braun, T. A., Darbro, B., Deluca, A. P., Kolbe, D. L., Scheetz, T. E., Shearer, A. E., Sompallae, R., Wang, K., Bassuk, A. G., Edens, E., Mathews, K., Moore, S. A., Shchelochkov, O. A., Trapane, P., Bossler, A., Campbell, C. A., Heusel, J. W., Kwitek, A., Maga, T., Panzer, K., Wassink, T., Van Daele, D., Azaiez, H., Booth, K., Meyer, N., Segal, M. M., Williams, M. S., Tromp, G., White, P., Corsmeier, D., Fitzgerald-Butt, S., Herman, G. , Lamb-Thrush, D. (2014) An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biology, 15(3) pp. R53.

Fang, Han, Wu, Yiyang, Narzisi, G., O'Rawe, Jason, Jimenez Barron, Laura, Rosenbaum, J., Ronemus, M., Iossifov, I., Schatz, M. C. , Lyon, Gholson J. (2014) Reducing INDEL calling errors in whole genome and exome sequencing data. Genome Med, 6(10) pp. 89.

Shi, L, Li, Bingbin, Huang, Y., Liu, T, Lyon, Gholson J., Xu, A , Wang, Kai (2014) "Genotype-first" approaches on a curious case of idiopathic progressive cognitive decline. BMC Med Genomics, 7(1) pp. 66.

O'Rawe, Jason, Fang, Han, Rynearson, Shawn, Robison, Reid J., Kiruluta, Edward S., Higgins, Gerald, Eilbeck, Karen, Reese, Martin G. , Lyon, Gholson J. (2013) Integrating precision medicine in the study and clinical treatment of a severely mentally ill person.. PeerJ, 1 pp. e177.

Wang, K., Kim, C., Bradfield, J., Guo, Y. F., Toskala, E., Otieno, F. G., Hou, C. P., Thomas, K., Cardinale, C., Lyon, G. J., Golhar, R. , Hakonarson, H. (2013) Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement. Genome Medicine, 5

O'Rawe, J., Jiang, T., Sun, G., Wu, Y., Wang, W., Hu, J., Bodily, P., Tian, L., Hakonarson, H., Johnson, W. E., Wei, Z., Wang, K. , Lyon, G. J. (2013) Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing. Genome Med, 5(3) pp. 28.

Lyon, Gholson J. , Segal, Jeremy P. (2013) Practical, ethical and regulatory considerations for the evolving medical and research genomics landscape.. Applied & Translational Genomics, 2(1) pp. 34-40. Elsevier.

Shi, L., Zhang, X., Golhar, R., Otieno, F. G., He, M., Hou, C., Kim, C., Keating, B., Lyon, G. J., Wang, K. , Hakonarson, H. (2013) Whole-genome sequencing in an autism multiplex family. Molecular Autism, 4(1) pp. 8.

Badner, J. A., Koller, D., Foroud, T., Edenberg, H., Nurnberger, J. I., Zandi, P. P., Willour, V. L., McMahon, F. J., Potash, J. B., Hamshere, M., Grozeva, D., Green, E., Kirov, G., Jones, I., Jones, L., Craddock, N., Morris, D., Segurado, R., Gill, M., Sadovnick, D., Remick, R., Keck, P., Kelsoe, J., Ayub, M., MacLean, A., Blackwood, D., Liu, C. Y., Gershon, E. S., McMahon, W., Lyon, G. J., Robinson, R., Ross, J. , Byerley, W. (2012) Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. Molecular Psychiatry, 17(8) pp. 818-826.

Elia, J., Glessner, J. T., Wang, K., Takahashi, N., Shtir, C. J., Hadley, D., Sleiman, P. M. A., Zhang, H., Kim, C. E., Robison, R., Lyon, G. J., Flory, J. H., Bradfield, J. P., Imielinski, M., Hou, C., Frackelton, E. C., Chiavacci, R. M., Sakurai, T., Rabin, C., Middleton, F. A., Thomas, K. A., Garris, M., Mentch, F., Freitag, C. M., Steinhausen, H. C., Todorov, A. A., Reif, A., Rothenberger, A., Franke, B., Mick, E. O., Roeyers, H., Buitelaar, J., Lesch, K. P., Banaschewski, T., Ebstein, R. P., Mulas, F., Oades, R. D., Sergeant, J., Sonuga-Barke, E., Renner, T. J., Romanos, M., Romanos, J., Warnke, A., Walitza, S., Meyer, J., Pálmason, H., Seitz, C., Loo, S. K., Smalley, S. L., Biederman, J., Kent, L., Asherson, P., Anney, R. J. L., Gaynor, J. W., Shaw, P., Devoto, M., White, P. S., Grant, S. F. A., Buxbaum, J. D., Rapoport, J. L., Williams, N. M., Nelson, S. F., Faraone, S. V. , Hakonarson, H. (2012) Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature Genetics, 44(1) pp. 78-84.

Lyon, G. J. (2012) Personalized medicine: Bring clinical standards to human-genetics research. Nature, 482(7385) pp. 300-301.

Lyon, G. J. (2012) There is nothing 'incidental' about unrelated findings. Personalized Medicine, 9(2) pp. 163-166.

Lyon, Gholson J. (2012) Guest post: Time to bring human genome sequencing into the clinic. genomesunzipped.org.

Lyon, Gholson J. , Wang, Kai (2012) Identifying disease mutations in genomic medicine settings: current challenges and how to accelerate progress. Genome Medicine, 4(7) pp. 58-58.

Scharf, J. M., Yu, D., Mathews, C. A., Neale, B. M., Stewart, S. E., Fagerness, J. A., Evans, P., Gamazon, E., Edlund, C. K., Service, S. K., Tikhomirov, A., Osiecki, L., Illmann, C., Pluzhnikov, A., Konkashbaev, A., Davis, L. K., Han, B., Crane, J., Moorjani, P., Crenshaw, A. T., Parkin, M. A., Reus, V. I., Lowe, T. L., Rangel-Lugo, M., Chouinard, S., Dion, Y., Girard, S., Cath, D. C., Smit, J. H., King, R. A., Fernandez, T. V., Leckman, J. F., Kidd, K. K., Kidd, J. R., Pakstis, A. J., State, M. W., Herrera, L. D., Romero, R., Fournier, E., Sandor, P., Barr, C. L., Phan, N., Gross-Tsur, V., Benarroch, F., Pollak, Y., Budman, C. L., Bruun, R. D., Erenberg, G., Naarden, A. L., Lee, P. C., Weiss, N., Kremeyer, B., Berrio, G. B., Campbell, D. D., Cardona Silgado, J. C., Ochoa, W. C., Mesa Restrepo, S. C., Muller, H., Valencia Duarte, A. V., Lyon, G. J., Leppert, M., Morgan, J., Weiss, R., Grados, M. A., Anderson, K., Davarya, S., Singer, H., Walkup, J., Jankovic, J., Tischfield, J. A., Heiman, G. A., Gilbert, D. L., Hoekstra, P. J., Robertson, M. M., Kurlan, R., Liu, C., Gibbs, J. R., Singleton, A., Hardy, J., Strengman, E., Ophoff, R. A., Wagner, M., Moessner, R., Mirel, D. B., Posthuma, D., Sabatti, C., Eskin, E., Conti, D. V., Knowles, J. A., Ruiz-Linares, A., Rouleau, G. A., Purcell, S., Heutink, P., Oostra, B. A., McMahon, W. M., Freimer, N. B., Cox, N. J. , Pauls, D. L. (2012) Genome-wide association study of Tourette's syndrome. Molecular Psychiatry, 18(6) pp. 721-728.

Lyon, Gholson J. (2011) Personal account of the discovery of a new disease using next-generation sequencing. Interview by Natalie Harrison. Pharmacogenomics, 12(11) pp. 1519-1523.

Lyon, Gholson J., Abi-Dargham, Anissa, Moore, Holly, Lieberman, Jeffrey A., Javitch, Jonathan A. , Sulzer, David (2011) Presynaptic regulation of dopamine transmission in schizophrenia. Schizophrenia Bulletin, 37(1) pp. 108-117.

Lyon, Gholson J., Jiang, Tao, Van Wijk, Richard, Wang, Wei, Bodily, Paul Mark, Xing, Jinchuan, Tian, Lifeng, Robison, Reid J., Clement, Mark, Lin, Yang, Zhang, Peng, Liu, Ying, Moore, Barry, Glessner, Joseph T., Elia, Josephine, Reimherr, Fred, van Solinge, Wouter W., Yandell, Mark, Hakonarson, Hakon, Wang, Jun, Johnson, William Evan, Wei, Zhi , Wang, Kai (2011) Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Dscovery Medicine, 12(62) pp. 41-55.

Rope, Alan F., Wang, Kai, Evjenth, Rune, Xing, Jinchuan, Johnston, Jennifer J., Swensen, Jeffrey J., Johnson, W. Evan, Moore, Barry, Huff, Chad D., Bird, Lynne M., Carey, John C., Opitz, John M., Stevens, Cathy A., Jiang, Tao, Schank, Christa, Fain, Heidi Deborah, Robison, Reid, Dalley, Brian, Chin, Steven, South, Sarah T., Pysher, Theodore J., Jorde, Lynn B., Hakonarson, Hakon, Lillehaug, Johan R., Biesecker, Leslie G., Yandell, Mark, Arnesen, Thomas , Lyon, Gholson J. (2011) Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. American Journal of Human Genetics, 89(1) pp. 28-43.

Wei, Zhi, Wang, Wei, Hu, Pingzhao, Lyon, Gholson J. , Hakonarson, Hakon (2011) SNVer: a statistical tool for variant calling in analysis of pooled or individual next-generation sequencing data. Nucleic Acids Research, 39(19) pp. e132.

Lyon, Gholson J., Samar, Stephanie M., Conelea, Christine, Trujillo, Marcel R., Lipinski, Christina M., Bauer, Christopher C., Brandt, Bryan C., Kemp, Joshua J., Lawrence, Zoe E., Howard, Jonathan, Castellanos, F. Xavier, Woods, Douglas , Coffey, Barbara J. (2010) Testing tic suppression: comparing the effects of dexmethylphenidate to no medication in children and adolescents with attention-deficit/hyperactivity disorder and Tourette's disorder. Journal of Child and Adolescent Psychopharmacology, 20(4) pp. 283-289.

Lyon, Gholson J., Shprecher, David, Coffey, Barbara , Kurlan, Roger (2010) Tourette's Disorder. Current Treatment Options in Neurology, 12(4) pp. 274-286.

Robison, R. J., Reimherr, F. W., Marchant, B. K., Kondo, D, Lyon, G. J., Olsen, J, Christopherson, D, Pommerville, C, Tuya, S, Johnson, A , Coon, H (2010) The Use of Emotional Dysregulation as an Endophenotype for Genetic studies in Adults with Attention-Deficit Hyperactivity Disorder. Journal of ADHD and Related Disorders, 1(4) pp. 29-38.

Lyon, G. J. , Coffey, B. J. (2009) Complex tics and complex management in a case of severe Tourette's disorder (TD) in an adolescent. Journal of Child and Adolescent Psychopharmacology, 19(4) pp. 469-74.

Lyon, Gholson J., Samar, Stephanie, Jummani, Rahil, Hirsch, Scott, Spirgel, Arie, Goldman, Rachel , Coffey, Barbara J. (2009) Aripiprazole in children and adolescents with Tourette's disorder: an open-label safety and tolerability study. Journal of Child and Adolescent Psychopharmacology, 19(6) pp. 623-633.

Lyon, G. J. , Coffey, B. (2008) Book Review: Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment, 3rd ed.. Journal of Clinical Psychiatry, 69(6) pp. 1023.

Lyon, G. J. , Coffey, B. (2008) Book Review: Treating Tourette Syndrome and Tic Disorders: A Guide for Practitioners. Journal of Child and Adolescent Psychopharmacology, 18(4) pp. 411-412.

Lyon, Gholson J. (2008) Possible varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline personality disorder, and methamphetamine abuse in remission. Journal of Clinical Psychopharmacology, 28(6) pp. 720-721.

Lyon, Gholson J., Coffey, Barbara , Silva, Raul (2008) Postraumatic stress disorder and reactive attachment disorder: outcome in an adolescent. Journal of Child and Adolescent Psychopharmacology, 18(6) pp. 641-646.

Lyon, G. J. , Koplewicz, H. S. (2007) Schizophrenia in childhood. The Scientist, 21(12 SUP) pp. 22-25.

Lyon, Gholson J. , Novick, Richard P. (2004) Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides, 25(9) pp. 1389-1403.

Wright, Jesse S., Lyon, Gholson J., George, Elizabeth A., Muir, Tom W. , Novick, Richard P. (2004) Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing. Proceedings of the National Academy of Sciences of the United States of America, 101(46) pp. 16168-16173.

Kalkum, Markus, Lyon, Gholson J. , Chait, Brian T. (2003) Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America, 100(5) pp. 2795-2800.

Lyon, Gholson J. , Muir, Tom W. (2003) Chemical signaling among bacteria and its inhibition. Chemistry & Biology, 10(11) pp. 1007-1021.

Miller, Justin S., Dudkin, Vadim Y., Lyon, Gholson J., Muir, Tom W. , Danishefsky, Samuel J. (2003) Toward fully synthetic N-linked glycoproteins. Angewandte Chemie International Edition, 42(4) pp. 431-434.

Lyon, Gholson J., Wright, Jesse S., Christopoulos, Arthur, Novick, Richard P. , Muir, Tom W. (2002) Reversible and specific extracellular antagonism of receptor-histidine kinase signaling. Journal of Biological Chemistry, 277(8) pp. 6247-6253.

Lyon, Gholson J., Wright, Jesse S., Muir, Tom W. , Novick, Richard P. (2002) Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus. Biochemistry, 41(31) pp. 10095-10104.

Jarraud, S., Lyon, G. J., Figueiredo, A. M., Lina, G., Gerard, L., Vandenesch, F., Etienne, J., Muir, T. W. , Novick, R. P. (2000) Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus. Journal of Bacteriology, 182(22) pp. 6517-6522.

Lyon, G. J., Mayville, P., Muir, T. W. , Novick, R. P. (2000) Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC. Proceedings of the National Academy of Sciences of the United States of America, 97(24) pp. 13330-13335.

Fuortes, M., Melchior, M., Han, H., Lyon, G. J. , Nathan, C. (1999) Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. Journal of Clinical Investigation, 104(3) pp. 327-335.

Hernandez, A., Lyon, G. J., Schneider, M. J. , St Germain, D. L. (1999) Isolation and characterization of the mouse gene for the type 3 iodothyronine deiodinase. Endocrinology, 140(1) pp. 124-130.

Gilmour, D. T., Lyon, G. J., Carlton, M. B., Sanes, J. R., Cunningham, J. M., Anderson, J. R., Hogan, B. L., Evans, M. J. , Colledge, W. H. (1998) Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens. Embo Journal, 17(7) pp. 1860-1870.

Hernandez, A., Park, J. P., Lyon, G. J., Mohandas, T. K. , St Germain, D. L. (1998) Localization of the type 3 iodothyronine deiodinase (DIO3) gene to human chromosome 14q32 and mouse chromosome 12F1. Genomics, 53(1) pp. 119-121.