The genome of the jellyfish Aurelia and the evolution of animal complexity

Gold, D. A., Katsuki, T., Li, Y., Yan, X., Regulski, M., Ibberson, D., Holstein, T., Steele, R. E., Jacobs, D. K., Greenspan, R. J. (December 2018) The genome of the jellyfish Aurelia and the evolution of animal complexity. Nat Ecol Evol, 3 (1). pp. 96-104. ISSN 2397-334x

URL: https://www.ncbi.nlm.nih.gov/pubmed/30510179
DOI: 10.1038/s41559-018-0719-8

Abstract

We present the genome of the moon jellyfish Aurelia, a genome from a cnidarian with a medusa life stage. Our analyses suggest that gene gain and loss in Aurelia is comparable to what has been found in its morphologically simpler relatives-the anthozoan corals and sea anemones. RNA sequencing analysis does not support the hypothesis that taxonomically restricted (orphan) genes play an oversized role in the development of the medusa stage. Instead, genes broadly conserved across animals and eukaryotes play comparable roles throughout the life cycle. All life stages of Aurelia are significantly enriched in the expression of genes that are hypothesized to interact in protein networks found in bilaterian animals. Collectively, our results suggest that increased life cycle complexity in Aurelia does not correlate with an increased number of genes. This leads to two possible evolutionary scenarios: either medusozoans evolved their complex medusa life stage (with concomitant shifts into new ecological niches) primarily by re-working genetic pathways already present in the last common ancestor of cnidarians, or the earliest cnidarians had a medusa life stage, which was subsequently lost in the anthozoans. While we favour the earlier hypothesis, the latter is consistent with growing evidence that many of the earliest animals were more physically complex than previously hypothesized.

Item Type: Paper
Subjects: organism description > animal
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > genomes
CSHL Authors:
Communities: CSHL labs > Ware lab
Depositing User: Matthew Dunn
Date: 3 December 2018
Date Deposited: 20 Dec 2018 16:35
Last Modified: 29 May 2019 19:25
Related URLs:
URI: https://repository.cshl.edu/id/eprint/37518

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