Sun, G., Krasnitz, A. (2019) CORE: A Software Tool for Delineating Regions of Recurrent DNA Copy Number Alteration in Cancer. Methods Mol Biol, 1878. pp. 85-93. ISSN 1064-3745
Abstract
Collections of genomic intervals are a common data type across many areas of computational biology. In cancer genomics, in particular, the intervals often represent regions with altered DNA copy number, and their collections exhibit recurrent features, characteristic of a given cancer type. Cores of Recurrent Events (CORE) is a versatile computational tool for identification of such recurrent features. Here we provide practical guidance for the use of CORE, implemented as an eponymous R package.
| Item Type: | Paper |
|---|---|
| Subjects: | bioinformatics diseases & disorders > cancer diseases & disorders diseases & disorders > neoplasms organism description > animal bioinformatics > genomics and proteomics > genetics & nucleic acid processing > genomes > comparative genomics bioinformatics > computational biology bioinformatics > genomics and proteomics > computers > computer software organism description > animal > mammal organism description > animal > mammal > rodent > mouse organism description > animal > mammal > rodent |
| CSHL Authors: | |
| Communities: | CSHL labs > Krasnitz lab CSHL Cancer Center Program > Cancer Genetics and Genomics Program |
| Depositing User: | Matthew Dunn |
| Date: | 2019 |
| Date Deposited: | 12 Nov 2018 21:48 |
| Last Modified: | 02 Feb 2024 21:02 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/37359 |
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