Localization of cellular proteins by enzymatic hydrolysis

Kaufmann, B. P., Gay, H., McDonald, M. R. (1950) Localization of cellular proteins by enzymatic hydrolysis. Cold Spring Harb Symp Quant Biol, 14. pp. 85-91. ISSN 0091-7451 (Print)0091-7451 (Linking)

URL: https://www.ncbi.nlm.nih.gov/pubmed/15442901
DOI: 10.1101/SQB.1950.014.01.012


Identification of types of cellular proteins and determination of their patterns of distribution and association with nucleic acids may be regarded as essential to an understanding of the processes involved in duplication of the living cell. A more specific evaluation of these processes with respect to replication of the gene complex requires precise information concerning the organization of the chromosome and the arrangement of its constituent materials during the various phases of mitosis. Inferences concerning the chemical composition of chromosomes derived from the earlier observations of descriptive cytologists have been supplemented in recent years by information provided by a variety of experimental procedures. Descriptions of patterns of linear organization in terms of achromatic and chromatic materials have accordingly been replaced by descriptions in terms of proteins and nucleic acids.

Item Type: Paper
Uncontrolled Keywords: *Chromosomes Humans Hydrolysis *Proteins
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell organization
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes
CSHL Authors:
Communities: The Carnegie Institution Department of Genetics
Depositing User: Matt Covey
Date: 1950
Date Deposited: 23 Jan 2018 16:31
Last Modified: 23 Jan 2018 16:31
Related URLs:
URI: https://repository.cshl.edu/id/eprint/35938

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