Kaufmann, B. P., Gay, H., McDonald, M. R. (1950) Localization of cellular proteins by enzymatic hydrolysis. Cold Spring Harb Symp Quant Biol, 14. pp. 85-91. ISSN 0091-7451 (Print)0091-7451 (Linking)
Abstract
Identification of types of cellular proteins and determination of their patterns of distribution and association with nucleic acids may be regarded as essential to an understanding of the processes involved in duplication of the living cell. A more specific evaluation of these processes with respect to replication of the gene complex requires precise information concerning the organization of the chromosome and the arrangement of its constituent materials during the various phases of mitosis. Inferences concerning the chemical composition of chromosomes derived from the earlier observations of descriptive cytologists have been supplemented in recent years by information provided by a variety of experimental procedures. Descriptions of patterns of linear organization in terms of achromatic and chromatic materials have accordingly been replaced by descriptions in terms of proteins and nucleic acids.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | *Chromosomes Humans Hydrolysis *Proteins |
| Subjects: | organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell organization bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes |
| CSHL Authors: | |
| Communities: | The Carnegie Institution Department of Genetics |
| Depositing User: | Matt Covey |
| Date: | 1950 |
| Date Deposited: | 23 Jan 2018 16:31 |
| Last Modified: | 23 Jan 2018 16:31 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/35938 |
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