Representational difference analysis: finding the differences between genomes

Lisitsyn, N. A. (August 1995) Representational difference analysis: finding the differences between genomes. Trends in Genetics, 11 (8). pp. 303-7. ISSN 0168-9525

DOI: 10.1016/S0168-9525(00)89087-3


Representational difference analysis (RDA) is an efficient method for finding the differences between complex genomes. The numerous applications of RDA include the cloning of probes for the detection of genetic lesions in cancer, the identification of sequences from the genomes of unknown pathogens and the rapid isolation of polymorphic markers linked to a trait without the use of pre-existing genetic maps.

Item Type: Paper
Uncontrolled Keywords: Animals Genetic Techniques Genome Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.
Subjects: organism description > animal
bioinformatics > genomics and proteomics > personal genomes
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > genomes > personal genomes
CSHL Authors:
Communities: CSHL labs
Depositing User: Jessica Koos
Date: August 1995
Date Deposited: 08 Aug 2014 20:06
Last Modified: 08 Aug 2014 20:06
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