Transcriptional activation by recruitment

Ptashne, Mark, Gann, Alexander (1997) Transcriptional activation by recruitment. Nature, 386 (6625). pp. 569-577.

URL: http://www.ncbi.nlm.nih.gov/pubmed/9121580
DOI: 10.1038/386569a0

Abstract

The recruitment model for gene activation stipulates that an activator works by bringing the transcriptional machinery to the DNA. Recent experiments in bacteria and yeast indicate that many genes can be activated by this mechanism. These findings have implications for our understanding of the nature of activating regions and their targets, and for the role of histones in gene regulation.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene regulation
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene regulation
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > transcription factor
CSHL Authors:
Communities: Watson School
Depositing User: Matt Covey
Date: 1997
Date Deposited: 23 Jun 2014 18:50
Last Modified: 23 Jun 2014 18:50
Related URLs:
URI: https://repository.cshl.edu/id/eprint/30330

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