Martienssen, R. (March 2001) Chipping away at chromatin. Nature Genetics, 27 (3). pp. 240-241. ISSN 1061-4036
DOI: 10.1038/85787
Abstract
When DNA-binding proteins are tethered to dam methylase from Escherichia coli. adenine methylation is directed to eukaryotic target sites in vivo. Hybridization of methylated DNA to microarrays allows binding sites to be displayed genome-wide, providing a versatile alternative to chromatin immunoprecipitation.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | in-vivo methyltransferase probe |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA methylation bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > DNA binding protein |
| CSHL Authors: | |
| Communities: | CSHL labs > Martienssen lab |
| Depositing User: | Matt Covey |
| Date: | March 2001 |
| Date Deposited: | 13 Dec 2013 16:18 |
| Last Modified: | 13 Dec 2013 16:18 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/28988 |
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