The flip side of synapse elimination

Zito, K. (January 2003) The flip side of synapse elimination. Neuron, 37 (1). pp. 1-2. ISSN 0896-6273 (Print)

Abstract

The fine tuning of synaptic circuits often requires an activity-dependent phase in which appropriate connections are strengthened and inappropriate connections are eliminated. In this issue of Neuron, Walsh and Lichtman propose a novel "synaptic takeover" mechanism for synapse elimination at the vertebrate NMJ, where withdrawal of one axon is accompanied by expansion of a competing axon into the newly vacated territory.

Item Type: Paper
Uncontrolled Keywords: Animals Cell Differentiation/ physiology Humans Motor Neurons/cytology/physiology Muscle, Skeletal/cytology/embryology/innervation Nervous System/cytology/ embryology Neuromuscular Junction/cytology/physiology Neuronal Plasticity/ physiology Presynaptic Terminals/physiology/ ultrastructure Synaptic Transmission/ physiology
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons
organs, tissues, organelles, cell types and functions > sub-cellular tissues: types and functions
organs, tissues, organelles, cell types and functions > sub-cellular tissues: types and functions > synapse
CSHL Authors:
Communities: CSHL labs > Svoboda lab
Depositing User: Matt Covey
Date: 9 January 2003
Date Deposited: 01 Jul 2013 19:17
Last Modified: 01 Jul 2013 19:17
Related URLs:
URI: https://repository.cshl.edu/id/eprint/27872

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