The flip side of synapse elimination

Zito, K. (January 2003) The flip side of synapse elimination. Neuron, 37 (1). pp. 1-2. ISSN 0896-6273 (Print)

Abstract

The fine tuning of synaptic circuits often requires an activity-dependent phase in which appropriate connections are strengthened and inappropriate connections are eliminated. In this issue of Neuron, Walsh and Lichtman propose a novel "synaptic takeover" mechanism for synapse elimination at the vertebrate NMJ, where withdrawal of one axon is accompanied by expansion of a competing axon into the newly vacated territory.

Item Type:	Paper
Uncontrolled Keywords:	Animals Cell Differentiation/ physiology Humans Motor Neurons/cytology/physiology Muscle, Skeletal/cytology/embryology/innervation Nervous System/cytology/ embryology Neuromuscular Junction/cytology/physiology Neuronal Plasticity/ physiology Presynaptic Terminals/physiology/ ultrastructure Synaptic Transmission/ physiology
Subjects:	organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons > neuronal circuits organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > sub-cellular tissues: types and functions organs, tissues, organelles, cell types and functions > sub-cellular tissues: types and functions > synapse
CSHL Authors:	Zito, Karen
Communities:	CSHL labs > Svoboda lab
Depositing User:	Matt Covey
Date:	9 January 2003
Date Deposited:	01 Jul 2013 19:17
Last Modified:	01 Jul 2013 19:17
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/27872

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