Spector, D. L.
(1993)
Nuclear organization of pre-mRNA processing.
Current Opinion in Cell Biology, 5 (3).
pp. 442-447.
ISSN 0955-0674
Abstract
Recent studies have suggested that small nuclear ribonucleoprotein particles (snRNPs), non-snRNP splicing factors, and several heterogeneous nuclear RNP proteins change their organization within the cell in response to transcriptional activity. Several of the RNA substrates with which these factors interact have been shown to localize in tracks that are associated with regions in which splicing factors are concentrated (nuclear speckles). It is now thought that pre-mRNA splicing may occur within these tracks.
| Item Type: |
Paper
|
| Uncontrolled Keywords: |
Animals
Cell Nucleus
Heterogeneous-Nuclear Ribonucleoproteins
Humans
RNA Polymerase II
RNA Precursors
RNA Processing, Post-Transcriptional
RNA Splicing
Ribonucleoproteins
Yeasts |
| Subjects: |
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > mRNA dynamics
organs, tissues, organelles, cell types and functions > organelles, types and functions > nucleus
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > pre-mRNA |
| CSHL Authors: |
|
| Communities: |
CSHL labs > Spector lab |
| Depositing User: |
Matt Covey
|
| Date: |
1993 |
| Date Deposited: |
10 Dec 2012 19:44 |
| Last Modified: |
29 Jan 2015 19:37 |
| URI: |
https://repository.cshl.edu/id/eprint/26325 |
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