A custody battle for the mind: evidence for extensive imprinting in the brain

Tollkuhn, J., Xu, X., Shah, N. M. (2010) A custody battle for the mind: evidence for extensive imprinting in the brain. Neuron, 67 (3). pp. 359-62. ISSN 1097-4199 (Electronic)0896-6273 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/20696374
DOI: 10.1016/j.neuron.2010.07.026

Abstract

Relatively few genes (approximately 100) have previously been shown to be imprinted such that their expression in progeny derives from either the maternal or paternal copy. Two recent studies by Gregg et al. (2010a, 2010b) in Science expand this list by an order of magnitude, revealing complex patterns of parent-of-origin bias in gene expression in the brain that are developmentally and regionally restricted, and in many cases, sexually dimorphic.

Item Type: Paper
Subjects: organs, tissues, organelles, cell types and functions > organs types and functions > brain
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene expression
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
CSHL Authors:
Communities: CSHL labs > Tollkuhn lab
Depositing User: Matt Covey
Date Deposited: 23 Jul 2015 19:21
Last Modified: 23 Jul 2015 19:21
Related URLs:
URI: http://repository.cshl.edu/id/eprint/31655

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