Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K., Foster, J. A., Penagarikano, O., Geschwind, D. H., Pacey, L. K., Hampson, D. R., Laliberte, C. L., Mills, A. A., Tam, E., Osborne, L. R., Kouser, M., Espinosa-Becerra, F., Xuan, Z., Powell, C. M., Raznahan, A., Robins, D. M., Nakai, N., Nakatani, J., Takumi, T., van Eede, M. C., Kerr, T. M., Muller, C., Blakely, R. D., Veenstra-VanderWeele, J., Henkelman, R. M., Lerch, J. P. (February 2015) 3D visualization of the regional differences. Mol Psychiatry, 20 (1). p. 1. ISSN 1359-4184
Abstract
We examined 26 different mouse models related to autism and identified three groups that shared similar neuroanatomical phenotypes. These three groups and their regional differences are shown here. Anything highlighted in red was determined to be larger in that group (median effect size for group >0.5) and anything highlighted in blue was determined to be smaller in that group (median effect size for group < − 0.5). These differences are shown in 3D in an axial representation either looking from above (a) or below (b) the mouse brain. For more information on this topic, please refer to the article by Ellegood et al on pages 118–125.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Brain/*anatomy & histology Imaging, Three-Dimensional/*methods Mice *Neuroimaging |
| Subjects: | diseases & disorders > mental disorders > personality disorders > autism Investigative techniques and equipment > brain atlas Investigative techniques and equipment > imaging |
| CSHL Authors: | |
| Communities: | CSHL labs > Mills lab |
| Depositing User: | Matt Covey |
| Date: | February 2015 |
| Date Deposited: | 02 Apr 2015 14:38 |
| Last Modified: | 02 Feb 2017 16:17 |
| PMCID: | PMC5131793 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/31308 |
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