Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing

Horowitz, D. S., Krainer, A. R. (March 1994) Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing. Trends in Genetics, 10 (3). pp. 100-106. ISSN 0168-9525

URL: http://www.ncbi.nlm.nih.gov/pubmed/8178363
DOI: 10.1016/0168-9525(94)90233-x

Abstract

Identification of 5' splice sites requires that limited and dispersed sequence information be interpreted precisely. Both snRNAs and proteins are required for this process. The selection of 5' splice sites in alternative splicing is closely related to that in constitutive splicing, and uses the same components in somewhat different ways.

Item Type: Paper
Uncontrolled Keywords: base-pairing interaction messenger-rna exon sequences alternative 5' u1 snrna invitro yeast factor-sf2 downstream regulators
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > pre-mRNA
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > splice site
organism description > yeast
CSHL Authors:
Communities: CSHL labs > Krainer lab
Depositing User: Matt Covey
Date: March 1994
Date Deposited: 11 Dec 2013 14:51
Last Modified: 11 Dec 2013 14:51
URI: http://repository.cshl.edu/id/eprint/28951

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