Analysing neuronal correlates of the comparison of two sequentially presented sensory stimuli

Brody, C. D., Hernandez, A., Zainos, A., Lemus, L., Romo, R. (December 2002) Analysing neuronal correlates of the comparison of two sequentially presented sensory stimuli. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences, 357 (1428). pp. 1843-1850. ISSN 0962-8436

URL: http://www.ncbi.nlm.nih.gov/pubmed/12626017
DOI: 10.1098/rstb.2002.1167

Abstract

In a typical sequential sensory discrimination task, subjects are required to make a decision based on comparing a sensory stimulus against the memory trace left by a previous stimulus. What is the neuronal substrate for such comparisons and the resulting decisions? This question was studied by recording neuronal responses in a variety of cortical areas of awake monkeys (Macaca mulatta), trained to carry out a vibrotactile sequential discrimination task. We describe methods to analyse responses obtained during the comparison and decision phases of the task, and describe the resulting findings from recordings in secondary somatosensory cortical area (S2). A subset of neurons in S2 become highly correlated with the monkey's decision in the task.

Item Type: Paper
Subjects: organism description > animal behavior
organs, tissues, organelles, cell types and functions > tissues types and functions > somatosensory cortex
CSHL Authors:
Communities: CSHL labs > Brody lab
Depositing User: Matt Covey
Date: December 2002
Date Deposited: 08 Jan 2014 22:26
Last Modified: 08 Jan 2014 22:26
PMCID: PMC1693076
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28679

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