Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia.

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia. [Video]

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Abstract

Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia. Regulatory T-lymphocytes (green), expressing EGFP as a fusion protein with the transcription factor Foxp3, are seen migrating in a live MMTV-PyMT;ACTB-ECFP;Foxp3EGFP mouse. The same field is shown during normoxia (21% inhaled oxygen), hypoxia (7% inhaled oxygen) and re-established normoxia (21% oxygen). Cancer cells are labeled blue. From Egeblad et al. (2008) Dis. Model. Mech., 1 155-167.

Item Type: Video
Subjects: diseases & disorders > cancer
diseases & disorders
Investigative techniques and equipment
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > T cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > T cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > T cells

organs, tissues, organelles, cell types and functions > cell types and functions > cell types
organs, tissues, organelles, cell types and functions > cell types and functions > cell types
organs, tissues, organelles, cell types and functions > cell types and functions > cell types

organs, tissues, organelles, cell types and functions > cell types and functions
Investigative techniques and equipment > microscopy > flourescence microscopy
Investigative techniques and equipment > microscopy > immunoflourescence microscopy
Investigative techniques and equipment > microscopy
organs, tissues, organelles, cell types and functions
CSHL Authors:
Communities: CSHL labs > Egeblad lab
Depositing User: Matt Covey
Date: 2008
Date Deposited: 26 Apr 2013 16:39
Last Modified: 26 Apr 2013 16:39
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28268

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