RNA interference: The new somatic cell genetics?

Paddison, P. J., Hannon, G. J. (2002) RNA interference: The new somatic cell genetics? Cancer Cell, 2 (1). pp. 17-23. ISSN 15356108 (ISSN)

URL: http://www.ncbi.nlm.nih.gov/pubmed/12150821
DOI: 10.1016/s1535-6108(02)00092-2

Abstract

RNAi is evolving into a powerful tool for manipulating gene expression in mammalian cells with potential utility for investigating gene function, for high-throughput, function-based genetic screens and potentially for development as a therapeutic tool. Copyright © 2002 Cell Press.

Item Type: Paper
Uncontrolled Keywords: RNA small interfering RNA bacteriophage T7 RNA polymerase DNA directed RNA polymerase double stranded RNA virus protein cell culture gene expression gene function gene sequence gene silencing high throughput screening human nonhuman oncogene priority journal review RNA interference somatic cell genetics animal biological model chemistry chromosome analysis genetics metabolism nucleotide sequence synthesis Mammalia Animals Base Sequence Cells, Cultured Cytogenetic Analysis DNA-Directed RNA Polymerases Humans Models, Genetic RNA, Double-Stranded RNA, Small Interfering Viral Proteins
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > design > nucleic acid design
Investigative techniques and equipment > RNAI
bioinformatics > genomics and proteomics > design > nucleic acid design > RNAI Design
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > RNAi
CSHL Authors:
Communities: CSHL labs > Hannon lab
Watson School > Publications
Depositing User: Matt Covey
Date: 2002
Date Deposited: 09 Jan 2013 16:57
Last Modified: 19 Sep 2014 14:14
Related URLs:
URI: http://repository.cshl.edu/id/eprint/26464

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