Nuclear organization of pre-mRNA processing

Spector, D. L. (1993) Nuclear organization of pre-mRNA processing. Current Opinion in Cell Biology, 5 (3). pp. 442-447. ISSN 0955-0674

URL: http://www.ncbi.nlm.nih.gov/pubmed/8352961

Abstract

Recent studies have suggested that small nuclear ribonucleoprotein particles (snRNPs), non-snRNP splicing factors, and several heterogeneous nuclear RNP proteins change their organization within the cell in response to transcriptional activity. Several of the RNA substrates with which these factors interact have been shown to localize in tracks that are associated with regions in which splicing factors are concentrated (nuclear speckles). It is now thought that pre-mRNA splicing may occur within these tracks.

Item Type: Paper
Uncontrolled Keywords: Animals Cell Nucleus Heterogeneous-Nuclear Ribonucleoproteins Humans RNA Polymerase II RNA Precursors RNA Processing, Post-Transcriptional RNA Splicing Ribonucleoproteins Yeasts
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > mRNA dynamics
organs, tissues, organelles, cell types and functions > organelles, types and functions > nucleus
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > pre-mRNA
CSHL Authors:
Communities: CSHL labs > Spector lab
Depositing User: Matt Covey
Date Deposited: 10 Dec 2012 19:44
Last Modified: 29 Jan 2015 19:37
URI: http://repository.cshl.edu/id/eprint/26325

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