Items where Subject is "mutagenesis"

A

Ando, S., Sarlis, N. J., Krishnan, J., Feng, X., Refetoff, S., Zhang, M. Q., Oldfield, E. H., Yen, P. M. (September 2001) Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance. Molecular Endocrinology, 15 (9). pp. 1529-1538. ISSN 0888-8809

Athma, P., Grotewold, E., Peterson, T. (May 1992) Insertional mutagenesis of the maize P gene by intragenic transposition of Ac. Genetics, 131 (1). pp. 199-209. ISSN 0016-6731 (Print)0016-6731 (Linking)

Autexier, C., Greider, C. W. (September 1995) Boundary elements of the Tetrahymena telomerase RNA template and alignment domains. Genes Dev, 9 (18). pp. 2227-39. ISSN 0890-9369 (Print)

Autexier, C., Greider, C. W. (February 1998) Mutational analysis of the Tetrahymena telomerase RNA: identification of residues affecting telomerase activity in vitro. Nucleic Acids Research, 26 (3). pp. 787-95. ISSN 0305-1048

B

Babb, R., Cleary, M. A., Herr, W. (December 1997) OCA-B is a functional analog of VP16 but targets a separate surface of the Oct-1 POU domain. Molecular and Cellular Biology, 17 (12). pp. 7295-305. ISSN 0270-7306 (Print)

Blasco, M. A., Funk, W., Villeponteau, B., Greider, C. W. (September 1995) Functional characterization and developmental regulation of mouse telomerase RNA. Science, 269 (5228). pp. 1267-70. ISSN 0036-8075 (Print)

Boles, M. K., Wilkinson, B. M., Maxwell, A., Lai, L., Mills, A. A., Nishijima, I., Salinger, A. P., Moskowitz, I., Hirschi, K. K., Liu, B., Bradley, A., Justice, M. J. (March 2009) A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet, 10 (1). p. 12.

C

Carmel, G., Kuret, J. (June 1992) A solid-phase screen for protein kinase substrate selectivity. Anal Biochem, 203 (2). pp. 274-80. ISSN 0003-2697 (Print)0003-2697 (Linking)

Chen, C. D., Kobayashi, R., Helfman, D. M. (March 1999) Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene. Genes and Development, 13 (5). pp. 593-606. ISSN 0890-9369 (Print)

Conlon, E. G., Fagegaltier, D., Agius, P., Davis-Porada, J., Gregory, J., Hubbard, I., Kang, K., Kim, D., Phatnani, H., Shneider, N. A., Manley, J. L., Kwan, J., Sareen, D., Broach, J. R., Simmons, Z., Arcila-Londono, X., Lee, E. B., Van Deerlin, V. M., Fraenkel, E., Ostrow, L. W., Baas, F., Zaitlen, N., Berry, J. D., Malaspina, A., Fratta, P., Cox, G. A., Thompson, L. M., Finkbeiner, S., Dardiotis, E., Miller, T. M., Chandran, S., Pal, S., Hornstein, E., Macgowan, D. J., Heiman-Patterson, T., Hammell, M. G., Patsopoulos, N. A., Dubnau, J., Nath, A., Phatnani, H., Shneider, N. A., Manley, J. L. (July 2018) Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. eLife, 7. ISSN 2050084X (ISSN)

Cottarel, G., Beach, D., Deuschle, U. (May 1993) 2 New Multipurpose Multicopy Schizosaccharomyces-Pombe Shuttle Vectors, Psp1 and Psp2. Current Genetics, 23 (5-6). pp. 547-548. ISSN 0172-8083

D

Dahmann, C., Futcher, B. (July 1995) Specialization of B-type cyclins for mitosis or meiosis in S. cerevisiae. Genetics, 140 (3). pp. 957-63. ISSN 0016-6731 (Print)

G

Geurts, A. M., Collier, L. S., Geurts, J. L., Oseth, L. L., Bell, M. L., Mu, David, Lucito, R., Godbout, S. A., Green, L. E., Lowe, S. W., Hirsch, B. A., Leinwand, L. A., Largaespada, D. A. (2006) Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. PLoS Genetics, 2 (9). pp. 1413-1423. ISSN 15537390

Green, S. R., Manche, L., Mathews, M. B. (January 1995) Two functionally distinct RNA-binding motifs in the regulatory domain of the protein kinase DAI. Mol Cell Biol, 15 (1). pp. 358-64. ISSN 0270-7306 (Print)

Guo, T., Hajdu, M., Agaram, N. P., Shinoda, H., Veach, D., Clarkson, B. D., Maki, R. G., Singer, S., Dematteo, R. P., Besmer, P., Antonescu, C. R. (November 2009) Mechanisms of sunitinib resistance in gastrointestinal stromal tumors harboring KITAY502-3ins mutation: an in vitro mutagenesis screen for drug resistance. Clin Cancer Res, 15 (22). pp. 6862-70. ISSN 1078-0432 (Print)1078-0432 (Linking)

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Hendelman, Anat, Zebell, Sophia, Rodriguez-Leal, Daniel, Dukler, Noah, Robitaille, Gina, Wu, Xuelin, Kostyun, Jamie, Tal, Lior, Wang, Peipei, Bartlett, Madelaine E, Eshed, Yuval, Efroni, Idan, Lippman, Zachary B (April 2021) Conserved pleiotropy of an ancient plant homeobox gene uncovered by cis-regulatory dissection. Cell, 184 (7). 1724-1739.e16. ISSN 0092-8674

Hinkley, C. S., Tanaka, M., Herr, W. (February 1994) Detailed Mutagenesis of a Reiterated 18-Amino-Acid Glutamine-Rich Activation Domain. Journal of Cellular Biochemistry. p. 31. ISSN 0730-2312

Huang, H., Ma, H. (February 1997) FON1, an Arabidopsis gene that terminates floral meristem activity and controls flower organ number. Plant Cell, 9 (2). pp. 115-34. ISSN 1040-4651 (Print)

I

Ipsaro, J. J., Shen, C., Arai, E., Xu, Y., Kinney, J. B., Joshua-Tor, L., Vakoc, C. R., Shi, J. (February 2017) Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis. PLoS One, 12 (2). e0172177. ISSN 1932-6203

J

Jenner, M., Kosol, S., Griffiths, D., Prasongpholchai, P., Manzi, L., Barrow, A. S., Moses, J. E., Oldham, N. J., Lewandowski, J. R., Challis, G. L. (March 2018) Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases. Nat Chem Biol, 14 (3). pp. 270-275. ISSN 1552-4450 (Print)1552-4450

K

Kuret, J., Johnson, K. E., Nicolette, C., Zoller, M. J. (July 1988) Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase. Isolation of site-directed mutants with altered binding affinity for catalytic subunit. J Biol Chem, 263 (19). pp. 9149-54. ISSN 0021-9258

L

Labrie, C., Morris, G. F., Mathews, M. B. (March 1993) A complex promoter element mediates transactivation of the human proliferating cell nuclear antigen promoter by the 243-residue adenovirus E1A oncoprotein. Mol Cell Biol, 13 (3). pp. 1697-707. ISSN 0270-7306 (Print)

Lai, J. S., Herr, W. (July 1997) Interdigitated residues within a small region of VP16 interact with Oct-1, HCF, and DNA. Molecular and Cellular Biology, 17 (7). pp. 3937-46. ISSN 0270-7306 (Print)

Li, Siran, Park, Sarah, Ye, Catherine, Danyko, Cassidy, Wroten, Matthew, Andrews, Peter, Wigler, Michael, Levy, Dan (July 2022) Targeted de novo phasing and long-range assembly by template mutagenesis. Nucleic Acids Research. ISSN 0305-1048

Lin, A., Giuliano, C. J., Sayles, N. M., Sheltzer, J. M. (March 2017) CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials. Elife, 6. e24179. ISSN 2050-084x

Liu, H., Jian, L., Xu, J., Zhang, Q., Zhang, M., Jin, M., Peng, Y., Yan, J., Han, B., Liu, J., Gao, F., Liu, X., Huang, L., Wei, W., Ding, Y., Yang, X., Li, Z., Zhang, M., Sun, J., Bai, M., Song, W., Chen, H., Sun, X., Li, W., Lu, Y., Liu, Y., Zhao, J., Qian, Y., Jackson, D., Fernie, A.R., Yan, J. (May 2020) High-Throughput CRISPR/Cas9 Mutagenesis Streamlines Trait Gene Identification in Maize. Plant Cell, 32 (5). pp. 1397-1413. ISSN 1040-4651

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Ma, Y., Mathews, M. B. (September 1996) Secondary and tertiary structure in the central domain of adenovirus type 2 VA RNA I. Rna, 2 (9). pp. 937-51. ISSN 1355-8382 (Print)

May, B. P., Liu, H., Vollbrecht, E., Senior, L., Rabinowicz, P. D., Roh, D., Pan, X. K., Stein, L., Freeling, M., Alexander, D., Martienssen, R. (September 2003) Maize-targeted mutagenesis: A knockout resource for maize. Proceedings of the National Academy of Sciences of the United States of America, 100 (20). pp. 11541-11546. ISSN 0027-8424

May, B. P., Martienssen, R. A. (2003) Transposon mutagenesis in the study of plant development. Critical Reviews in Plant Sciences, 22 (1). pp. 1-35. ISSN 0735-2689

Mi, S., Alonso, D., Roberts, R. J. (February 1995) Functional analysis of Gln-237 mutants of HhaI methyltransferase. Nucleic Acids Res, 23 (4). pp. 620-7. ISSN 0305-1048 (Print)

Moore, J. M., Calzada, J. P., Gagliano, W., Grossniklaus, U. (1997) Genetic characterization of hadad, a mutant disrupting female gametogenesis in Arabidopsis thaliana. Cold Spring Harbor Symposia on Quantitative Biology, 62. pp. 35-47. ISSN 0091-7451 (Print)

Muskett, P. R., Clissold, L., Marocco, A., Springer, P. S., Martienssen, R., Dean, C. (June 2003) A resource of mapped dissociation launch pads for targeted insertional mutagenesis in the Arabidopsis genome. Plant physiology, 132 (2). pp. 506-16. ISSN 0032-0889 (Print)0032-0889 (Linking)

O

O'Farrell, P. A., Joshua-Tor, L. (January 2007) Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure. Biochem J, 401 (2). pp. 421-8. ISSN 0264-6021 (Public Dataset)

R

Regan, M. C., Zhu, Z., Yuan, H., Myers, S. J., Menaldino, D. S., Tahirovic, Y. A., Liotta, D. C., Traynelis, S. F., Furukawa, H. (January 2019) Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors. Nat Commun, 10 (1). p. 321. ISSN 2041-1723

S

Schneider, B. L., Steiner, B., Seufert, W., Futcher, A. B. (February 1996) pMPY-ZAP: a reusable polymerase chain reaction-directed gene disruption cassette for Saccharomyces cerevisiae. Yeast, 12 (2). pp. 129-34. ISSN 0749-503X (Print)

Selvakumar, M., Helfman, D. M. (March 1999) Exonic splicing enhancers contribute to the use of both 3' and 5' splice site usage of rat beta-tropomyosin pre-mRNA. Rna, 5 (3). pp. 378-94. ISSN 1355-8382 (Print)

Sheldon, M., Ratnasabapathy, R., Hernandez, N. (February 1993) Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs. Mol Cell Biol, 13 (2). pp. 1251-63. ISSN 0270-7306 (Print)

Sheltzer, J. M., Blank, H. M., Pfau, S. J., Tange, Y., George, B. M., Humpton, T. J., Brito, I. L., Hiraoka, Y., Niwa, O., Amon, A. (August 2011) Aneuploidy drives genomic instability in yeast. Science, 333 (6045). pp. 1026-30. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

Sher, Falak, Hossain, Mir, Seruggia, Davide, Schoonenberg, Vivien AC, Yao, Qiuming, Cifani, Paolo, Dassama, Laura MK, Cole, Mitchel A, Ren, Chunyan, Vinjamur, Divya S, Macias-Trevino, Claudio, Luk, Kevin, McGuckin, Connor, Schupp, Patrick G, Canver, Matthew C, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Wolfe, Scot A, Pinello, Luca, Maeda, Takahiro, Kentsis, Alex, Orkin, Stuart H, Bauer, Daniel E (July 2019) Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. Nature Genetics, 51 (7). pp. 1149-1159. ISSN 1061-4036

Steiner, B. R., Hidaka, K., Futcher, B. (April 1996) Association of the Est1 protein with telomerase activity in yeast. Proceedings of the National Academy of Sciences of the United States of America, 93 (7). pp. 2817-21. ISSN 0027-8424

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Tansey, William P., Herr, Winship (February 1997) Selective use of TBP and TFIIB revealed by a TATA-TBP-TFIIB array with altered specificity. Science, 275 (5301). pp. 829-31. ISSN 0036-8075 (Print)

Taylor, D. R., Lee, S. B., Romano, P. R., Marshak, D. R., Hinnebusch, A. G., Esteban, M., Mathews, M. B. (November 1996) Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR. Molecular and Cellular Biology, 16 (11). pp. 6295-302. ISSN 0270-7306

W

Wang, Zihua, Moffitt, Andrea B, Andrews, Peter, Wigler, Michael, Levy, Dan (September 2022) Accurate measurement of microsatellite length by disrupting its tandem repeat structure. Nucleic Acids Research. gkac723. ISSN 0305-1048

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Yu, A., Saudemont, B., Bouteiller, N., Elvira-Matelot, E., Lepere, G., Parent, J. S., Morel, J. B., Cao, J., Elmayan, T., Vaucheret, H. (August 2015) Second site mutagenesis of a hypomorphic ago1 allele identifies SKI3 as an endogenous suppressor of PTGS. Plant Physiol. ISSN 1532-2548 (Electronic)0032-0889 (Linking)