Gray, G Kenneth, Carlson, Eric G, Lev, Tatyana, Marshall, Bailey, Reed, Austin D, Sánchez-Covarrubias, Alex P, Twigger, Alecia-Jane, Puig-Barbe, Aleix, Thennavan, Aatish, Omotoso, Ayodele, Murrow, Lyndsay M, Chatterjee, Deeptiman, He, Siyuan, Pensa, Sara, Aevermann, Brian, Tavares, Norbert K, Chen, Natalie, Hilton, Jason A, Blake, Kerrigan, Liu, Yunlong, Phong, Kiet, Gartner, Zev J, Lawson, Devon A, Swarbrick, Alexander, Dos Santos, Camila O, George, Sophia HL, Brugge, Joan S, LaBarge, Mark A, Nakshatri, Harikrishna, Navin, Nicholas, Kessenbrock, Kai, Khaled, Walid T (September 2025) Defining breast epithelial cell types in the single-cell era. Developmental Cell, 60 (17). pp. 2218-2236. ISSN 1534-5807
Abstract
Single-cell studies on breast tissue have contributed to a change in our understanding of breast epithelial diversity that has, in turn, precipitated a lack of consensus on breast cell types. The confusion surrounding this issue highlights a possible challenge for advancing breast atlas efforts. In this perspective, we present our consensus on the identities, properties, and naming conventions for breast epithelial cell types and propose goals for future atlas endeavors. Our proposals and their underlying thought processes aim to catalyze the adoption of a shared model for this tissue and to serve as guidance for other investigators facing similar challenges.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > cancer diseases & disorders diseases & disorders > cancer > cancer types > breast cancer diseases & disorders > cancer > cancer types |
| CSHL Authors: | |
| Communities: | CSHL labs > Dos Santos lab |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 8 September 2025 |
| Date Deposited: | 12 Sep 2025 12:49 |
| Last Modified: | 12 Sep 2025 12:49 |
| PMCID: | PMC12425455 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/41959 |
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