Banerjee, Arkarup, Chen, Feng, Druckmann, Shaul, Long, Michael A (January 2023) Neural dynamics in the rodent motor cortex enables flexible control of vocal timing. bioRxiv. (Submitted)
Preview |
PDF
2023_Banerjee_Neural_dynamics_in_the_rodent_motor_cortex_preprint.pdf - Submitted Version Available under License Creative Commons Attribution Non-commercial No Derivatives. Download (3MB) | Preview |
Abstract
Neocortical activity is thought to mediate voluntary control over vocal production, but the underlying neural mechanisms remain unclear. In a highly vocal rodent, the Al-ston’s singing mouse, we investigate neural dynamics in the orofacial motor cortex (OMC), a structure critical for vocal behavior. We first describe neural activity that is modulated by component notes (approx. 100 ms), likely representing sensory feed-back. At longer timescales, however, OMC neurons exhibit diverse and often persistent premotor firing patterns that stretch or compress with song duration (approx. 10 s). Using computational modeling, we demonstrate that such temporal scaling, acting via downstream motor production circuits, can enable vocal flexibility. These results provide a framework for studying hierarchical control circuits, a common design principle across many natural and artificial systems.
| Item Type: | Paper |
|---|---|
| Subjects: | organs, tissues, organelles, cell types and functions > tissues types and functions > motor cortex organism description > animal > mammal > rodent |
| CSHL Authors: | |
| Communities: | CSHL labs > Banerjee lab |
| SWORD Depositor: | CSHL Elements |
| Depositing User: | CSHL Elements |
| Date: | 23 January 2023 |
| Date Deposited: | 29 Sep 2023 18:18 |
| Last Modified: | 29 Sep 2023 18:18 |
| PMCID: | PMC9900850 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/41077 |
Actions (login required)
 |
Administrator's edit/view item |