The growing applications of click chemistry

Moses, J. E., Moorhouse, A. D. (August 2007) The growing applications of click chemistry. Chemical Society Reviews, 36 (8). pp. 1249-1262. ISSN 0306-0012

URL: https://...
DOI: 10.1039/b613014n


Click chemistry, the subject of this tutorial review, is a modular synthetic approach towards the assembly of new molecular entities. This powerful strategy relies mainly upon the construction of carbon-heteroatom bonds using spring-loaded reactants. Its growing number of applications are found in nearly all areas of modern chemistry from drug discovery to materials science. The copper(I)-catalysed 1,2,3-triazole forming reaction between azides and terminal alkynes has become the gold standard of click chemistry due to its reliability, specificity and biocompatibility.

Item Type: Paper
CSHL Authors:
Depositing User: Matthew Dunn
Date: August 2007
Date Deposited: 17 Nov 2020 21:32
Last Modified: 17 Nov 2020 21:32

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