Wu, X.S., Vakoc, C. R. (May 2020) A Pliable ERα Cistrome Evades Therapy. Nat Cell Biol, 22 (6). pp. 619-620. ISSN 1465-7392
Abstract
The transcription factor oestrogen receptor alpha (ERα) has long been targeted for therapeutic benefit in cancer, but drug resistance can emerge through a multitude of mechanisms. A study now reveals how the ERα cistrome can become reprogrammed to confer resistance to tamoxifen in breast cancer.
| Item Type: | Paper |
|---|---|
| Subjects: | bioinformatics bioinformatics > genomics and proteomics > genetics & nucleic acid processing bioinformatics > genomics and proteomics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification bioinformatics > genomics and proteomics > small molecules > estrogen bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types bioinformatics > genomics and proteomics > small molecules bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > transcription factor |
| CSHL Authors: | |
| Communities: | CSHL labs > Vakoc lab |
| Depositing User: | Adrian Gomez |
| Date: | 18 May 2020 |
| Date Deposited: | 21 May 2020 17:00 |
| Last Modified: | 01 Feb 2024 19:29 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/39470 |
Actions (login required)
 |
Administrator's edit/view item |
