Pettersson, U., Mulder, C., Deluis, H., Sharp, P. A. (January 1973) Cleavage of adenovirus type 2 DNA into six unique fragments by endonuclease R-RI. Proc Natl Acad Sci U S A, 70 (1). pp. 200-4.
Abstract
The DNA of adenovirus type 2 was cleaved by restriction endonuclease R·RI into six fragments. These fragments were separated by electrophoresis on composite agarose-polyacrylamide gels. Their molecular weights ranged from 1.1 × 106 to 13.6 × 106, as measured by electron microscopy. Each fragment represented a unique segment of adenovirus type 2 DNA since: (i) the fragments were obtained in equimolar amounts; (ii) the sum of their molecular weights was equal to the molecular weight of complete adenovirus DNA; and (iii) each fragment exhibited a rate of renaturation that was inversely proportional to its size.
| Item Type: | Paper |
|---|---|
| Subjects: | organism description > virus > adenovirus |
| CSHL Authors: | |
| Communities: | CSHL labs |
| Depositing User: | Elizabeth Pessala |
| Date: | January 1973 |
| Date Deposited: | 11 Dec 2018 15:42 |
| Last Modified: | 11 Dec 2018 15:42 |
| PMCID: | PMC433215 |
| URI: | https://repository.cshl.edu/id/eprint/37397 |
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