Ponder, Eric (1937) The spherical form of the mammalian erythrocyte: III. Changes in surface area in disks and spheres. Journal of Experimental Biology, 14 (3). pp. 267-277.
Abstract
Red cells placed in hypotonic media swell until a certain "critical volume" is reached, after which the cell haemolyses. Shortly before reaching this critical volume, the cell becomes a perfect sphere, and in hypotonic serum the area of the sphere is substantially the same as the area of the disk in an isotonic medium. Thus the increase in cell volume is not accompanied by an increase in cell surface, but rather by a change in cell shape, and lysis occurs when the volume has increased to such an extent that the cell membrane is subject to stretching forces. In hypotonic NaCl the critical volume is smaller than it is in hypotonic plasma, and the cell haemolyses before its membrane is subject to extension.
| Item Type: | Paper |
|---|---|
| Subjects: | organism description > animal > mammal organs, tissues, organelles, cell types and functions > cell types and functions > cell types > red blood cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types > red blood cells organs, tissues, organelles, cell types and functions > cell types and functions > cell types > red blood cells |
| CSHL Authors: | |
| Communities: | The Biological Laboratory |
| Depositing User: | Elizabeth Pessala |
| Date: | 1937 |
| Date Deposited: | 30 Oct 2017 18:41 |
| Last Modified: | 24 Jul 2018 15:59 |
| URI: | https://repository.cshl.edu/id/eprint/35628 |
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