Kazmi, S. A., Bukhari, A. I. (July 1978) A mutant of Escherichia coli which accumulates large amounts of coproporphyrin. Biochim Biophys Acta, 541 (3). pp. 420-4. ISSN 0006-3002 (Print)0006-3002 (Linking)
Abstract
A mutant of Escherichia coli which accumulates a large amount of coproporphyrin, presumably because of a block in heme biosynthesis, has been isolated after nitrosoguanidine mutagenesis. On rich media, the mutant forms colonies which give bright orange fluorescence when illuminated with ultraviolet light. The mutant appears to be similar to a Salmonella typhimurium mutant, deficient in uroporphyrinogen III cosynthase, described by Sasarman and Desrochers ((1976) J. Bacteriol. 128, 717--721). A striking property of the mutant is that coproporphyrin is retained within the cells in rich media but is almost totally excreted out of cells in minimal glucose medium.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Coproporphyrins/*metabolism Culture Media Escherichia coli/*genetics/growth & development/metabolism Glucose/metabolism Methylnitronitrosoguanidine Mutation Porphyrins/*metabolism |
| Subjects: | organism description > bacteria > escherichia coli |
| CSHL Authors: | |
| Communities: | CSHL labs |
| Depositing User: | Matt Covey |
| Date: | 3 July 1978 |
| Date Deposited: | 14 Oct 2016 19:50 |
| Last Modified: | 14 Oct 2016 19:50 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/33316 |
Actions (login required)
 |
Administrator's edit/view item |