Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry

Malinauskas, Tomas, Furukawa, Hiro (May 2016) Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry. Structure, 24 (5). pp. 653-655. ISSN 0969-2126

Abstract

Signal transduction across cell membranes often requires assembly of heteromeric receptors with defined stoichiometry. In this issue of Structure, Morales-Perez et al. (2016) present elegant methods for the expression of heteromeric nicotinic acetylcholine receptors with a defined α4β2 stoichiometry involving controlled baculovirus-mediated transduction and subunit counting by measurement of two fluorescent signals.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > NMDA receptor
organs, tissues, organelles, cell types and functions > tissues types and functions > signal transduction
CSHL Authors:
Communities: CSHL labs > Furukawa lab
Depositing User: Matt Covey
Date: 3 May 2016
Date Deposited: 09 May 2016 19:16
Last Modified: 30 Oct 2017 18:43
PMCID: PMC5266497
Related URLs:
URI: https://repository.cshl.edu/id/eprint/32784

Actions (login required)

Administrator's edit/view item Administrator's edit/view item