Genetic analysis of adenovirus type 2. IX. The physical locations of structural genes

Weber, J., Hassell, J. A. (September 1979) Genetic analysis of adenovirus type 2. IX. The physical locations of structural genes. J Gen Virol, 44 (3). pp. 639-55. ISSN 0022-1317 (Print)0022-1317 (Linking)

DOI: 10.1099/0022-1317-44-3-639


Several virus-specified proteins of adenovirus type 2 (Ad2) and type 5 (Ad5) can be distinguished by their differential electrophoretic mobility in SDS-polyacrylamide gels. By comparing the physical maps of the genomes of interserotypic recombinants between ts mutants of these viruses with the pattern of proteins expressed, the physical locations of some genes can be determined on the adenovirus DNA molecule. The proteins of a total of 103 recombinants were analysed; 44 of these are of known DNA structure. Structural genes for the proteins analysed span the following loci on the conventional adenovirus map: V (30 to 43); III (43 to 44); II and 66K (55 to 57); 100K, 36K, 32K (69 to 71); IV (80 to 90).

Item Type: Paper
Uncontrolled Keywords: Adenoviruses, Human/analysis/*genetics DNA, Viral/analysis *Genes *Genes, Viral Mutation Peptides/genetics Recombination, Genetic Viral Proteins/genetics
Subjects: organism description > virus > adenovirus
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
CSHL Authors:
Communities: CSHL labs
Depositing User: Matt Covey
Date: September 1979
Date Deposited: 09 May 2016 16:20
Last Modified: 09 May 2016 16:20
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