Futcher, A. B. (August 1991) Saccharomyces cerevisiae cell cycle: cdc28 and the G1 cyclins. Semin Cell Biol, 2 (4). pp. 205-12. ISSN 1043-4682 (Print)1043-4682 (Linking)
Abstract
Two families of cyclin-like proteins have been found in S. cerevisiae. The clb proteins are the mitotic cyclins. The cln proteins provide an essential function, are required for the G1/S transition, and appear to be rate-limiting for START, but have no obvious role elsewhere in the cycle. The cln proteins are unstable; they form complexes with cdc28; the complexes have protein kinase activity; and at least one of the clns oscillates in abundance through the cell cycle. The action of the cln cyclins at START suggests that they may be 'G1 cyclins'.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | CDC28 Protein Kinase, S cerevisiae/*physiology Cell Cycle/physiology Cyclins/*physiology G1 Phase/physiology Mitosis/physiology Saccharomyces cerevisiae/cytology/enzymology/*physiology |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > Cyclins organism description > yeast > Saccharomyces organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell cycle organism description > yeast |
| CSHL Authors: | |
| Communities: | CSHL labs > Futcher lab |
| Depositing User: | Matt Covey |
| Date: | August 1991 |
| Date Deposited: | 21 Dec 2015 15:40 |
| Last Modified: | 21 Dec 2015 15:40 |
| URI: | https://repository.cshl.edu/id/eprint/32140 |
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