Tyers, M., Fitch, I., Tokiwa, G., Dahmann, C., Nash, R., Linskens, M., Futcher, B. (1991) Characterization of G1 and mitotic cyclins of budding yeast. Cold Spring Harb Symp Quant Biol, 56. pp. 21-32. ISSN 0091-7451 (Print)0091-7451 (Linking)
Abstract
It has been known for a decade that in yeast, the CDC28 gene of Saccharomyces cerevisiae and the cdc2+ gene of Schizosaccharomyces pombe are needed at two points in their host's cell cycles: once in G1 phase, for commitment to division, and once again in mitosis (Nurse and Bissett 1981; Piggott et al. 1982). These two genes encode highly homologous proteins, which have proven to be the catalytic subunits of protein kinases (Reed et al. 1985; Simanis and Nurse 1986). The active protein kinase is a complex containing the Cdc28/cdc2 protein and a protein called a cyclin (Draetta et al. 1989). Other subunits may also be present (Brizuela et al. 1987.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Amino Acid Sequence Cyclins/genetics/*metabolism Genes, Fungal Interphase/genetics/*physiology Mitosis/genetics/*physiology Models, Biological Molecular Sequence Data Mutation Peptides/pharmacology Protein Kinases/genetics/metabolism Protein Tyrosine Phosphatases/metabolism Saccharomyces cerevisiae/*cytology/genetics/metabolism Sequence Homology, Nucleic Acid |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > Cyclins organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell cycle organs, tissues, organelles, cell types and functions > organelles, types and functions > mitosis organism description > yeast |
| CSHL Authors: | |
| Communities: | CSHL labs > Futcher lab |
| Depositing User: | Matt Covey |
| Date: | 1991 |
| Date Deposited: | 14 Jan 2016 15:12 |
| Last Modified: | 14 Jan 2016 15:12 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/32053 |
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