Olson, L. E., Dasen, J. S., Ju, B. G., Tollkuhn, J., Rosenfeld, M. G. (2003) Paired-like repression/activation in pituitary development. Recent Prog Horm Res, 58. pp. 249-61. ISSN 0079-9963 (Print)0079-9963 (Linking)
Abstract
Pituitary gland development is controlled by signals that guide expression of specific combinations of transcription factors that dictate serial determination and differentiation events. One class of factors is paired-like homeodomain factors. Two that have been investigated are the repressor Hex1/Rpx and activator prophet of Pit-1 (Prop-1), which exert selective roles during pituitary development. The opposing actions of these factors provide one aspect of pituitary organogenesis.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Animals Basic Helix-Loop-Helix Transcription Factors Homeodomain Proteins/genetics/ physiology Humans Mutation Organogenesis Pituitary Gland/embryology/ growth & development |
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > homeodomain protein organs, tissues, organelles, cell types and functions > tissues types and functions > suprachiasmatic nucleus > hypothalamus organs, tissues, organelles, cell types and functions > tissues types and functions > hypothalamus organs, tissues, organelles, cell types and functions > tissues types and functions > pituitary gland |
| CSHL Authors: | |
| Communities: | CSHL labs > Tollkuhn lab |
| Depositing User: | Matt Covey |
| Date: | 2003 |
| Date Deposited: | 23 Jul 2015 19:02 |
| Last Modified: | 23 Jul 2015 19:02 |
| URI: | https://repository.cshl.edu/id/eprint/31661 |
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